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1. WO2020108600 - A NOVEL BLANK LIPOSOME WITH GINSENOSIDE RG3 OR ITS ANALOG AS MEMBRANE MATERIALS AND PREPARATIONS AND USES THEREOF

Publication Number WO/2020/108600
Publication Date 04.06.2020
International Application No. PCT/CN2019/121880
International Filing Date 29.11.2019
IPC
A61K 9/127 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61K 47/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
A61K 45/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 8/63 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
63Steroids; Derivatives thereof
A61Q 19/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
CPC
A61K 31/337
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
337having four-membered rings, e.g. taxol
A61K 31/4745
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
4738ortho- or peri-condensed with heterocyclic ring systems
4745condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
A61K 31/704
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034attached to a carbocyclic compound, e.g. phloridzin
704attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
A61K 33/243
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
243Platinum; Compounds thereof
A61K 47/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
A61K 8/63
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
63Steroids; Derivatives thereof
Applicants
  • SHANGHAI GINSOME PHARMATECH CO., LTD. [CN]/[CN]
Inventors
  • WANG, Jianxin
  • HONG, Chao
  • ZHU, Ying
  • XIA, Jiaxuan
  • WANG, Dan
  • CHEN, Yingjiang
  • ZHAN, Huaxing
Agents
  • SHANGHAI BESHINING LAW OFFICE
Priority Data
201811447243.429.11.2018CN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A NOVEL BLANK LIPOSOME WITH GINSENOSIDE RG3 OR ITS ANALOG AS MEMBRANE MATERIALS AND PREPARATIONS AND USES THEREOF
(FR) NOUVEAU LIPOSOME VIDE COMPRENANT LE GINSÉNOSIDE RG3 OU SON ANALOGUE EN TANT QUE MATÉRIAUX DE MEMBRANE, ET PRÉPARATIONS ET UTILISATIONS CORRESPONDANTES
Abstract
(EN)
The present invention provides a blank liposome with ginsenoside Rg3 or its anaglog as the membrane material, preparations and uses thereof. The disclosed blank liposome has a membrane comprising a lipid and a ginsenoside analog of Formula (I), presenting remarkable advantages in film formation, encapsulation efficiency, targeted drug delivery, blood circulation time, stability, safety and homogeneity. It can also be used to load active substances of drugs and cosmetics, biological agents, polynucleotides or oligonucleotides, and the preparation process is convenient.
(FR)
La présente invention concerne un liposome vide comprenant le ginsénoside Rg3 ou son analogue en tant que matériau de membrane, ainsi que des préparations et des utilisations correspondantes. Le liposome vide de l'invention possède une membrane comprenant un lipide et un analogue du ginsénoside de formule I, présentant des avantages remarquables quant à la formation de film, l'efficacité d'encapsulation, l'administration ciblée de médicament, le temps de circulation sanguine, la stabilité, la sécurité d'emploi et l'homogénéité. Il peut également être utilisé pour charger des substances actives médicamenteuses et cosmétiques, des agents biologiques, des polynucléotides ou des oligonucléotides, et le processus de préparation est pratique.
Also published as
Latest bibliographic data on file with the International Bureau