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1. WO2020108519 - SYSTEM AND METHOD FOR INTEGRATION OF BIOLOGICAL CHIPS

Publication Number WO/2020/108519
Publication Date 04.06.2020
International Application No. PCT/CN2019/121226
International Filing Date 27.11.2019
IPC
G01N 33/53 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
C12Q 1/68 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
G01N 33/53
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
Applicants
  • MGI TECH CO., LTD. [CN]/[CN]
Inventors
  • WANG, Liang
  • GONG, Jian
  • LIN, Yan-You
  • LI, Shifeng
Agents
  • SYNCLAW ATTORNEYS
Priority Data
62/772,47728.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SYSTEM AND METHOD FOR INTEGRATION OF BIOLOGICAL CHIPS
(FR) SYSTÈME ET PROCÉDÉ D'INTÉGRATION DE PUCES BIOLOGIQUES
Abstract
(EN)
An apparatus (100) including multiple biological chips (110,120) includes a substrate (101), a first adhesive layer (134) disposed on the substrate (101), a first biological chip (110) and a second biological chip (120) disposed on the first adhesive layer (134) and attached to the substrate (101) by the adhesive layer (134). The apparatus (100)further includes a filler (130) disposed between the first biological chip (110) and the second biological chip (120). The filler (130) includes a second adhesive layer (135) extending between a side surface (114) of the first biological chip (110) and a side surface (124) of the second biological chip (120), the second adhesive layer (135) attaching the first biological chip (110) to the second biological chip (120). The filler (130) also includes a surface layer (132) disposed over the second adhesive layer (135). The surface layer (132) has a hydrophobic surface that is co-planar with a top surface (111) of the first biological chip (110) and a top surface (121) of the second biological chip (120).
(FR)
L'invention concerne un appareil (100) comprenant de multiples puces biologiques (110, 120), qui comprend un substrat (101), une première couche adhésive (134) disposée sur le substrat (101), une première puce biologique (110) et une seconde puce biologique (120) disposées sur la première couche adhésive (134) et fixées au substrat (101) par la couche adhésive (134). L'appareil (100) comprend en outre une charge (130) disposée entre la première puce biologique (110) et la seconde puce biologique (120). La charge (130) comprend une seconde couche adhésive (135) s'étendant entre une surface latérale (114) de la première puce biologique (110) et une surface latérale (124) de la seconde puce biologique (120), la seconde couche adhésive (135) fixant la première puce biologique (110) à la seconde puce biologique (120). La charge (130) comprend également une couche de surface (132) disposée sur la seconde couche adhésive (135). La couche de surface (132) possède une surface hydrophobe qui est coplanaire avec une surface supérieure (111) de la première puce biologique (110) et une surface supérieure (121) de la seconde puce biologique (120).
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