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1. WO2020108154 - SALT FORM OF ESTROGEN RECEPTOR DOWNREGULATOR, CRYSTALLINE FORM THEREOF, AND PREPARATION METHOD THEREFOR

Publication Number WO/2020/108154
Publication Date 04.06.2020
International Application No. PCT/CN2019/111624
International Filing Date 17.10.2019
IPC
C07D 209/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
04Indoles; Hydrogenated indoles
10with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
A61K 31/404 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 31/404
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 209/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
04Indoles; Hydrogenated indoles
10with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applicants
  • 罗欣药业(上海)有限公司 LUOXIN PHARMACEUTICAL (SHANGHAI) CO., LTD. [CN]/[CN]
  • 山东罗欣药业集团股份有限公司 SHANDONG LUOXIN PHARMACEUTICAL GROUP STOCK CO., LTD. [CN]/[CN]
Inventors
  • 贺辉君 HE, Huijun
  • 施沈一 SHI, Shenyi
  • 陆剑宇 LU, Jianyu
  • 丁照中 DING, Charles Z.
  • 胡利红 HU, Lihong
  • 施斌 SHI, Bin
  • 杨文谦 YANG, Wenqian
  • 董加强 DONG, Jiaqiang
  • 王铁林 WANG, Tie-Lin
Agents
  • 上海弼兴律师事务所 SHANGHAI BESHINING LAW OFFICE
Priority Data
201811434915.828.11.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) SALT FORM OF ESTROGEN RECEPTOR DOWNREGULATOR, CRYSTALLINE FORM THEREOF, AND PREPARATION METHOD THEREFOR
(FR) FOME SALINE D’UN DOWN-RÉGULATEUR RÉCEPTEUR DES OESTROGÈNES
(ZH) 一种雌激素受体下调剂的盐型、晶型及其制备方法
Abstract
(EN)
Provided are a salt form of an estrogen receptor downregulator, a crystalline form thereof, and a preparation method therefor.
(FR)
L’invention concerne une fome saline d’un down-régulateur récepteur des oestrogènes, sa forme cristalline et son procédé de préparation.
(ZH)
一种雌激素受体下调剂的盐型、晶型及其制备方法被公开,所述盐型和晶型可治疗乳腺癌。
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