Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020108117 - METHOD FOR PREPARING ESCITALOPRAM BIS-HYDROXYNAPHTOATE CRYSTAL FORM A

Publication Number WO/2020/108117
Publication Date 04.06.2020
International Application No. PCT/CN2019/110807
International Filing Date 12.10.2019
IPC
C07D 307/87 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77ortho- or peri-condensed with carbocyclic rings or ring systems
87Benzo furans; Hydrogenated benzo furans
CPC
C07D 307/87
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77ortho- or peri-condensed with carbocyclic rings or ring systems
87Benzo [c] furans; Hydrogenated benzo [c] furans
Applicants
  • 浙江华海药业股份有限公司 ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD [CN]/[CN]
  • 上海奥博生物医药技术有限公司 SHANGHAI AOBO PHARMTECH, INC., LTD. [CN]/[CN]
Inventors
  • 许炜 XU, Wei
  • 陈茜 CHEN, Xi
  • 顾虹 GU, Hong
Agents
  • 北京柏杉松知识产权代理事务所(普通合伙) PATENTSINO IP FIRM
Priority Data
201811212608.526.11.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) METHOD FOR PREPARING ESCITALOPRAM BIS-HYDROXYNAPHTOATE CRYSTAL FORM A
(FR) PROCÉDÉ DE PRÉPARATION D'UNE FORME CRISTALLINE A D'ESCITALOPRAM BIS-HYDROXYNAPHTOATE
(ZH) 一种艾司西酞普兰双羟萘酸盐晶型A的制备方法
Abstract
(EN)
Provided herein is a method for preparing an Escitalopram bis-hydroxynaphtoate ((S)-(+)-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)) -1, 3-dihydro-5-cyanisobenzofuranone) crystal form A. Said method is ecofriendly and non pollutive, and the obtained Escitalopram bis-hydroxynaphtoate crystal form A is highly pure and easy to reproduce.
(FR)
L'invention concerne un procédé de préparation d'une forme cristalline A d'Escitalopram bis-hydroxynaphtoate ((S)-(+)-1-(3-(diméthylamino)propyle)-1-(4-fluorophényle))-1,3-dihydro-5-cyanisobenzofuranone). Ce procédé est écologique et non polluant et la forme cristalline A d'Escitalopram bis-hydroxynaphtoate ainsi obtenue est très pure et facile à reproduire.
(ZH)
本申请涉及一种艾司西酞普兰双羟萘酸盐((S)-(+)-1-〔3-(二甲胺基)丙基〕-1-(4-氟苯基)-1,3-二氢-5-氰基异苯并呋喃双羟萘酸盐)晶型A新的制备方法,所述方法环保,无污染,采用所述方法制得的艾司西酞普兰双羟萘酸盐晶型A纯度高,重复性好。
Also published as
Latest bibliographic data on file with the International Bureau