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1. WO2020107820 - JOINT CAVITY INJECTION PREPARATION AND USE THEREOF

Publication Number WO/2020/107820
Publication Date 04.06.2020
International Application No. PCT/CN2019/087849
International Filing Date 21.05.2019
IPC
A61K 31/723 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
716Glucans
723Xanthans
A61K 31/728 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
726Glycosaminoglycans, i.e. mucopolysaccharides
728Hyaluronic acid
A61K 9/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
C08B 37/02 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
BPOLYSACCHARIDES; DERIVATIVES THEREOF
37Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
02Dextran; Derivatives thereof
A61P 19/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
CPC
A61K 31/723
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
716Glucans
723Xanthans
A61K 9/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
A61K 9/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
C08B 37/0033
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
BPOLYSACCHARIDES; DERIVATIVES THEREOF
37Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
0024beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
0033Xanthan, i.e. D-glucose, D-mannose and D-glucuronic acid units, saubstituted with acetate and pyruvate, with a main chain of (beta-1,4)-D-glucose units; Derivatives thereof
Applicants
  • 山东省药学科学院 SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES [CN]/[CN]
  • 山东福瑞达医药集团有限公司 SHANDONG FREDA PHARMACEUTICAL GROUP CO., LTD. [CN]/[CN]
Inventors
  • 凌沛学 LING, Peixue
  • 刘飞 LIU, Fei
  • 邵华荣 SHAO, Huarong
  • 陈磊 CHEN, Lei
  • 张治云 ZHANG, Zhiyun
  • 张晓元 ZHANG, Xiaoyuan
  • 陈启鑫 CHEN, Qixin
  • 韩冠英 HAN, Guanying
  • 程艳玲 CHENG, Yanling
  • 张建强 ZHANG, Jianqiang
  • 张岱州 ZHANG, Daizhou
Agents
  • 北京君慧知识产权代理事务所(普通合伙) BEIJING JUNHUI INTELLECTUAL PROPERTY AGENT OFFICE (ORDINARY PARTNERSHIP)
Priority Data
201811455378.530.11.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) JOINT CAVITY INJECTION PREPARATION AND USE THEREOF
(FR) PRÉPARATION D'INJECTION DE CAVITÉ ARTICULAIRE ET UTILISATION ASSOCIÉE
(ZH) 一种关节腔注射制剂及其应用
Abstract
(EN)
Disclosed is a joint cavity injection preparation and a use thereof. The joint cavity injection preparation uses deacetylated xanthan gum, and has better biocompatibility and a higher safe dosage range compared with existing xanthan gum joint cavity injection preparations.
(FR)
L'invention concerne une préparation d'injection de cavité articulaire et son utilisation. La préparation d'injection de cavité articulaire utilise de la gomme xanthane désacétylée, et présente une meilleure biocompatibilité et une plage posologique plus sûre par comparaison avec des préparations d'injection de cavité articulaire de gomme xanthane existantes.
(ZH)
一种关节腔注射制剂及其应用。该关节腔注射制剂采用脱乙酰黄原胶,与现有黄原胶关节腔注射制剂相比,具有更好的生物相容性,安全剂量范围更高。
Also published as
Latest bibliographic data on file with the International Bureau