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1. WO2020099777 - USE OF AN ORGANOMETALLIC COMPOUND AS A DNA-DEMETHYLATING AGENT

Publication Number WO/2020/099777
Publication Date 22.05.2020
International Application No. PCT/FR2019/052689
International Filing Date 12.11.2019
IPC
A61K 8/49 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
A61Q 19/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
A61Q 19/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
06for countering cellulitis
A61K 8/19 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
A61K 31/295 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
28Compounds containing heavy metals
295Iron group metal compounds
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • UNIVERSITE DE LORRAINE [FR]/[FR]
  • INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE - INSERM [FR]/[FR]
Inventors
  • GRANDEMANGE, Stéphanie
  • MONARI, Antonio
  • GROS, Philippe
  • CARTRON, Pierre François
Agents
  • LE CACHEUX, Samuel
  • CHAUVIN, Vincent
  • ORSINI, Fabienne
  • BLAYO, Nadine
  • BONNANS, Arnaud
  • CANUEL, Clélia
  • DE CACQUERAY-VALMENIER, Stanislas
  • LE BIHAN, Jean-Michel
  • LIENARD, Céline
  • DEVIC, David
  • CELLIER, Pascal
  • MAGUER, Aude
Priority Data
186041212.11.2018FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) USE OF AN ORGANOMETALLIC COMPOUND AS A DNA-DEMETHYLATING AGENT
(FR) UTILISATION D'UN COMPOSE ORGANOMETALLIQUE EN TANT QU'AGENT DE DEMETHYLATION DE L'ADN
Abstract
(EN)
The invention relates to the non-therapeutic use, as a DNA-demethylating agent, of at least one organometallic compound comprising an iron atom bound to two terpyridine groups. The invention also relates to an organometallic compound comprising an iron atom bound to two terpyridine groups, to be used as a drug.
(FR)
L'invention concerne l'utilisation non-thérapeutique, en tant qu'agent de déméthylation de l'ADN, d'au moins un composé organométallique comprenant un atome de fer lié à deux groupes terpyridines. L'invention porte également sur un composé organométallique comprenant un atome de fer lié à deux groupes terpyridines pour son utilisation comme médicament.
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