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1. WO2020097054 - TREATING NON-ALCOHOLIC STEATOHEPATITIS WITH CCK INHIBITORS

Publication Number WO/2020/097054
Publication Date 14.05.2020
International Application No. PCT/US2019/059833
International Filing Date 05.11.2019
IPC
A61K 31/221 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
221with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
A61K 31/465 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
465Nicotine; Derivatives thereof
A61K 31/4748 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
4748forming part of bridged ring systems
CPC
A61K 31/195
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
A61K 31/355
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
355Tocopherols, e.g. vitamin E
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants
  • GEORGETOWN UNIVERSITY [US]/[US]
Inventors
  • SMITH, Jill P.
Agents
  • MCKEON, Tina Williams
  • FERNANDEZ, Lizette M.
Priority Data
62/756,38406.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TREATING NON-ALCOHOLIC STEATOHEPATITIS WITH CCK INHIBITORS
(FR) TRAITEMENT DE LA STÉATOHÉPATITE NON ALCOOLIQUE AVEC DES INHIBITEURS DE LA CCK
Abstract
(EN)
Provided herein are methods for treating nonalcoholic steatohepatitis (NASH) in a subject, comprising administering to a subject having NASH an effective amount of a CCK receptor inhibitor.
(FR)
L'invention concerne des méthodes de traitement de la stéatohépatite non alcoolique (SHNA) chez un sujet, consistant à administrer une quantité efficace d'un inhibiteur du récepteur de la CCK à un sujet ayant une SHNA.
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