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1. WO2020096871 - NOVEL SUBSTITUTED TRICYCLIC COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS

Publication Number WO/2020/096871
Publication Date 14.05.2020
International Application No. PCT/US2019/059296
International Filing Date 01.11.2019
IPC
C07D 235/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
C07D 487/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • MERCK SHARP & DOHME CORP. [US]/[US]
  • HAN, Yongxin [CA]/[US] (US)
  • BENNETT, David Jonathan [GB]/[US] (US)
  • BHARATHAN, Indu [US]/[US] (US)
  • GUO, Liangqin [US]/[US] (US)
  • HOPKINS, Brett, A. [US]/[US] (US)
  • HUANG, Xianhai [CN]/[US] (US)
  • LI, Derun [CN]/[US] (US)
  • LU, Min [CN]/[US] (US)
  • PASTERNAK, Alexander [US]/[US] (US)
  • SLOMAN, David, L. [US]/[US] (US)
  • ZHANG, Hongjun [US]/[US] (US)
  • ZHOU, Hua [CN]/[US] (US)
Inventors
  • HAN, Yongxin
  • BENNETT, David Jonathan
  • BHARATHAN, Indu
  • GUO, Liangqin
  • HOPKINS, Brett, A.
  • HUANG, Xianhai
  • LI, Derun
  • LU, Min
  • PASTERNAK, Alexander
  • SLOMAN, David, L.
  • ZHANG, Hongjun
  • ZHOU, Hua
Common Representative
  • MERCK SHARP & DOHME CORP.
Priority Data
62/756,29906.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL SUBSTITUTED TRICYCLIC COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS
(FR) NOUVEAUX COMPOSÉS TRICYCLIQUES SUBSTITUÉS UTILISÉS EN TANT QU'INHIBITEURS DE L'INDOLÉAMINE 2,3-DIOXYGÉNASE
Abstract
(EN)
Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: Formula (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
(FR)
L'invention concerne des composés de formule (I) qui sont des inhibiteurs d'une enzyme IDO : Formule (I). L'invention concerne également des utilisations des composés dans le traitement ou la prévention potentiels d'une maladie ou d'un trouble associé à l'IDO. L'invention concerne également des compositions comprenant ces composés. L'invention concerne en outre des utilisations des compositions dans le traitement ou la prévention potentiels d'une maladie ou d'un trouble associé à l'IDO.
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