Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020096682 - USE OF TUMOR INFLITRATING LYMPHOCYTES FOR TREATING NSCLC PATIENTS REFRACTORY FOR ANTI-PD-1 ANTIBODY

Publication Number WO/2020/096682
Publication Date 14.05.2020
International Application No. PCT/US2019/049384
International Filing Date 03.09.2019
IPC
A61K 35/17 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
14Blood; Artificial blood
17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
A61K 45/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C12N 5/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • IOVANCE BIOTHERAPEUTICS, INC. [US]/[US]
Inventors
  • FARDIS, Maria
  • NATARAJAN, Arvind
Agents
  • MACDOUGALL, Christina, A.
  • ESKER, Todd
  • BEARDELL, Louis
  • GE, Xinquan
  • ANTCZAK, Andrew, J.
Priority Data
62/725,97631.08.2018US
62/726,91904.09.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF TUMOR INFLITRATING LYMPHOCYTES FOR TREATING NSCLC PATIENTS REFRACTORY FOR ANTI-PD-1 ANTIBODY
(FR) TRAITEMENT DE PATIENTS SOUFFRANT DE NSCLC RÉFRACTAIRES À UN ANTICORPS ANTI-PD-1
Abstract
(EN)
The present invention provides improved and/or shortened processes and methods for preparing TILs in order to prepare therapeutic populations of TILs with increased therapeutic efficacy for the treatment of non-small cell lung carcinoma (NSCLC), wherein the NSCLC is refractory to treatment with an anti -PD- 1 antibody.
(FR)
La présente invention concerne des processus améliorés et/ou raccourcis et des procédés de préparation de TIL afin de préparer des populations thérapeutiques de TIL ayant une efficacité thérapeutique accrue pour le traitement d'un carcinome pulmonaire non à petites cellules (CPNPC), le CPNPC étant réfractaire à un traitement avec un anticorps anti-PD-1.
Latest bibliographic data on file with the International Bureau