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1. WO2020095974 - TRANSPLANT AND USE THEREOF

Publication Number WO/2020/095974
Publication Date 14.05.2020
International Application No. PCT/JP2019/043582
International Filing Date 07.11.2019
IPC
A61P 3/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 43/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A61F 2/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02Prostheses implantable into the body
28Bones
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 35/12 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
A61K 35/39 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
37Digestive system
39Pancreas; Islets of Langerhans
Applicants
  • 国立大学法人東京大学 THE UNIVERSITY OF TOKYO [JP]/[JP]
Inventors
  • 竹内 昌治 TAKEUCHI Shoji
  • 小沢 文智 OZAWA Fumisato
  • 長田 翔伍 NAGATA Shogo
Agents
  • 棚井 澄雄 TANAI Sumio
  • 飯田 雅人 IIDA Masato
  • 大浪 一徳 ONAMI Kazunori
Priority Data
2018-21128809.11.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) TRANSPLANT AND USE THEREOF
(FR) GREFFON ET UTILISATION CORRESPONDANTE
(JA) 移植片及びその使用
Abstract
(EN)
This transplant comprises: a shell part that comes into contact with a body fluid when the transplant is transplanted into a live body; and a core part that is located inside the shell part and substantially does not come into contact with the body fluid. The core part includes a plurality of first hydrogel fiber including cells, and the shell part includes a second hydrogel functioning as a semi-permeable film. The transplant has an outer diameter of greater than 1.5 mm.
(FR)
L'invention concerne un greffon comprenant : une partie coque qui vient en contact avec un fluide corporel lorsque le greffon est transplanté dans un corps vivant ; et une partie noyau qui est située à l'intérieur de la partie coque et ne vient pratiquement pas en contact avec le fluide corporel. La partie noyau comprend une pluralité de premières fibres d'hydrogel comprenant des cellules et la partie coque comprend un deuxième hydrogel servant de film semi-perméable. Le greffon présente un diamètre externe supérieur à 1,5 mm.
(JA)
移植片であって、前記移植片は、生体内に移植された場合に体液に接触するシェル部と、前記シェル部の内部に位置し、前記体液とは実質的に接触しないコア部とを有し、前記コア部は細胞を含む複数の第1のハイドロゲルファイバを含み、前記シェル部は半透膜として機能する第2のハイドロゲルを含み、前記移植片は外径1.5mmを超える大きさを有する、移植片。
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