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1. WO2020095000 - MICROFLUIDIC SAMPLE PREPARATION DEVICE OFFERING HIGH REPEATABILITY

Publication Number WO/2020/095000
Publication Date 14.05.2020
International Application No. PCT/FR2019/052660
International Filing Date 07.11.2019
IPC
G01N 1/38 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation
38Diluting, dispersing or mixing samples
B01F 13/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
13Other mixers; Mixing plant, including combinations of dissimilar mixers
B01J 19/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
B01L 3/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
B01F 11/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
11Mixers with shaking, oscillating, or vibrating mechanisms
B01F 15/04 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
15Accessories for mixers
04Forming a predetermined ratio of the substances to be mixed
Applicants
  • COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES [FR]/[FR]
  • HORIBA ABX SAS [FR]/[FR]
Inventors
  • FOUILLET, Yves
  • ALI-CHERIF, Anais
Agents
  • AHNER, Philippe
Priority Data
186040309.11.2018FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) MICROFLUIDIC SAMPLE PREPARATION DEVICE OFFERING HIGH REPEATABILITY
(FR) DISPOSITIF MICROFLUIDIQUE DE PREPARATION D'ECHANTILLONS OFFRANT UNE GRANDE REPETABILITE
Abstract
(EN)
Disclosed is a device for preparing a solution from a sample and a reagent, comprising a microfluidic array comprising a sample supply inlet (E1), a reagent supply inlet (E2), a discharge outlet (S1), a solution collection outlet (S2), a sampling zone (ZE) to which the inlets (E1, E2) are connected, first (4) and second (6) preparation chambers connected to the sampling zone (ZE), arranged to either side of the sampling zone (ZE) such that the liquid flowing from one preparation chamber to the other flows through the first sampling zone (ZE), the first preparation chamber (4) having a volume that is variable between a minimum volume and a calibrated volume. The device comprises valves interrupting the flow of the fluid at least at the two inlets (E1, E2) and the collection (S2) and discharge (S1) outlets.
(FR)
Dispositif de préparation d'une solution à partir d'un échantillon et d'un réactif, comportant un réseau microfluidique comprenant une entrée d'alimentation (E1) en un échantillon,une entrée d'alimentation (E2) en un réactif, une sortie d'évacuation (S1), une sortie de collecte (S2) de la solution, une zone d'échantillonnage (ZE) à laquelle sont connectées les entrées(E1, E2), des première (4) et deuxième (6) chambres de préparation connectées à la zone d'échantillonnage(ZE), disposées de part et d'autre de la zone d'échantillonnage (ZE) de sorte que le liquide circulant d'une chambre de préparation à l'autre circule dans la première zone d'échantillonnage (ZE), la première chambre de préparation (4) étant à volume variable entre un volume minimal et un volume calibré. Le dispositif comporte des vannes interrompant la circulation du fluide au moins au niveau des deux entrées(E1, E2)et des sorties de collecte (S2) et d'évacuation(S1).
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