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1. WO2020094744 - ANTIBODY FORMULATION

Publication Number WO/2020/094744
Publication Date 14.05.2020
International Application No. PCT/EP2019/080445
International Filing Date 06.11.2019
IPC
C07K 16/10 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
Applicants
  • GENMAB A/S [DK]/[DK]
  • BIONTECH SE [DE]/[DE]
Inventors
  • ALTINTAS, Isil
  • SATIJN, David
  • RADEMAKER, Rik
  • PARREN, Paul
  • SAHIN, Ugur
  • GIESEKE, Friederikke
  • MUIK, Alexander
Agents
  • GENMAB A/S
Priority Data
PCT/EP2018/08036906.11.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTIBODY FORMULATION
(FR) FORMULATION D'ANTICORPS
Abstract
(EN)
The present invention relates to pharmaceutical formulations of binding agents and their use in medicine. In particular, the invention relates to pharmaceutical formulations of binding agents such as bispecific antibodies binding human PD-L1 and binding human CD137. The invention furthermore relates to uses of the pharmaceutical formulations of the invention and to methods for producing pharmaceutical formulations.
(FR)
La présente invention concerne des formulations pharmaceutiques d'agents de liaison et leur utilisation en médecine. En particulier, l'invention concerne des formulations pharmaceutiques d'agents de liaison tels que des anticorps bispécifiques de liaison au PD-L1 humain et de liaison au CD137 humain. L'invention concerne en outre des utilisations des formulations pharmaceutiques de l'invention et des procédés de production de formulations pharmaceutiques.
Latest bibliographic data on file with the International Bureau