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1. WO2020094613 - NOD2 INHIBITORS FOR THE TREATMENT OF HEREDITARY PERIODIC FEVERS

Publication Number WO/2020/094613
Publication Date 14.05.2020
International Application No. PCT/EP2019/080183
International Filing Date 05.11.2019
IPC
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/4706 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
47064-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
A61P 43/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A61P 37/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
G01N 33/48 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
Applicants
  • INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) [FR]/[FR]
  • UNIVERSITÉ DE LILLE [FR]/[FR]
  • INSTITUT PASTEUR DE LILLE [FR]/[FR]
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) [FR]/[FR]
  • UNIVERSITY OF HOHENHEIM [DE]/[DE]
Inventors
  • CHAMAILLARD, Mathias
  • POULIN, Lionel
  • NORMAND, Sylvain
  • KUFER, Thomas Alexander
Agents
  • INSERM TRANSFERT
Priority Data
18306453.406.11.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOD2 INHIBITORS FOR THE TREATMENT OF HEREDITARY PERIODIC FEVERS
(FR) INHIBITEURS DE NOD2 POUR LE TRAITEMENT DE FIÈVRES PÉRIODIQUES HÉRÉDITAIRES
Abstract
(EN)
The present invention relates to methods and pharmaceutical compositions for the treatment of hereditary periodic fevers. In particular, the present invention relates to a method for treating hereditary periodic fevers in a subject in need thereof comprising administering the subject with a therapeutically effective amount of at least one inhibitor of NOD2-mediated signaling pathway.
(FR)
La présente invention concerne des procédés et des compositions pharmaceutiques pour le traitement de fièvres périodiques héréditaires. En particulier, la présente invention concerne un procédé de traitement de fièvres périodiques héréditaires chez un sujet en ayant besoin, comprenant l'administration au sujet d'une quantité thérapeutiquement efficace d'au moins un inhibiteur de la voie de signalisation médiée par NOD2.
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