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1. WO2020094591 - PDE10A INHIBITORS FOR TREATING NEGATIVE SYMPTOMS AND COGNITIVE IMPAIRMENTS IN A PATIENT SUFFERING FROM SCHIZOPHRENIA

Publication Number WO/2020/094591
Publication Date 14.05.2020
International Application No. PCT/EP2019/080151
International Filing Date 05.11.2019
IPC
A61K 31/4985 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
A61K 31/4709 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
4709Non-condensed quinolines containing further heterocyclic rings
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61P 25/18 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Applicants
  • H. LUNDBECK A/S [DK]/[DK]
Inventors
  • NIELSEN, Jacob
  • BULLER, Raimund
Priority Data
19189762.802.08.2019EP
PA20180082506.11.2018DK
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PDE10A INHIBITORS FOR TREATING NEGATIVE SYMPTOMS AND COGNITIVE IMPAIRMENTS IN A PATIENT SUFFERING FROM SCHIZOPHRENIA
(FR) INHIBITEURS DE PDE10A POUR LE TRAITEMENT DE SYMPTÔMES NÉGATIFS ET DE TROUBLES COGNITIFS CHEZ UN PATIENT SOUFFRANT DE SCHIZOPHRÉNIE
Abstract
(EN)
The present invention relates to PDE10A inhibitors and compositions comprising PDE10A inhibitors for treating negative symptoms, persistent negative symptoms, prominent negative symptoms, persistent prominent negative symptoms, predominant negative symptoms, persistent predominant negative symptoms and/or cognitive dysfunctions in schizophrenia.
(FR)
La présente invention concerne des inhibiteurs de PDE10A et des compositions comprenant des inhibiteurs de PDE10A pour traiter des symptômes négatifs, des symptômes négatifs persistants, des symptômes négatifs proéminents, des symptômes négatifs proéminents persistants, des symptômes négatifs prédominants, des symptômes négatifs prédominants persistants et/ou des dysfonctionnements cognitifs dans la schizophrénie.
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