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1. WO2020094111 - RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF

Publication Number WO/2020/094111
Publication Date 14.05.2020
International Application No. PCT/CN2019/116453
International Filing Date 08.11.2019
IPC
C07D 403/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
14containing three or more hetero rings
C07D 401/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14containing three or more hetero rings
C07D 409/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
409Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
14containing three or more hetero rings
A61K 31/506 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
506not condensed and containing further heterocyclic rings
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 27/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
Applicants
  • 北京泰德制药股份有限公司 BEIJING TIDE PHARMACEUTICAL CO., LTD. [CN]/[CN]
Inventors
  • 赵焰平 ZHAO, Yanping
  • 王红军 WANG, Hongjun
  • 李功 LI, Gong
  • 姜媛媛 JIANG, Yuanyuan
  • 李想 LI, Xiang
  • 刘彬 LIU, Bin
  • 刘凯 LIU, Kai
  • 仲伟婷 ZHONG, Weiting
  • 李发洁 LI, Fajie
  • 赵静 ZHAO, Jing
  • 庞建梅 PANG, Jianmei
  • 周丽莹 ZHOU, Liying
Agents
  • 北京永新同创知识产权代理有限公司 NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD.
Priority Data
PCT/CN2018/11480109.11.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF
(FR) INHIBITEUR DE PROTÉINE KINASE ASSOCIÉE À RHO, COMPOSITION PHARMACEUTIQUE LE COMPRENANT ET SON UTILISATION
(ZH) Rho相关蛋白激酶抑制剂、包含其的药物组合物及其用途
Abstract
(EN)
A Rho-associated protein kinase (ROCK) inhibitor represented by formula (I), a pharmaceutical composition comprising same, and a use thereof for preventing or treating ROCK-mediated diseases.
(FR)
L'invention concerne un inhibiteur de protéine kinase associée à Rho (ROCK) représenté par la formule (I), une composition pharmaceutique le comprenant, et une utilisation de celui-ci pour prévenir ou traiter des maladies médiées par ROCK.
(ZH)
式(I)的Rho相关蛋白激酶抑制剂、包含其的药物组合物、及其用于预防或治疗Rho相关蛋白激酶(ROCK)介导的疾病的用途。
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