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1. WO2020093060 - LASER THERAPY FOR TREATMENT AND PREVENTION OF EYE DISEASES

Publication Number WO/2020/093060
Publication Date 07.05.2020
International Application No. PCT/US2019/059709
International Filing Date 04.11.2019
IPC
A61F 9/008 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
007Methods or devices for eye surgery
008using laser
CPC
A61F 2009/00865
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
007Methods or devices for eye surgery
008using laser
00861adapted for treatment at a particular location
00865Sclera
A61F 2009/00868
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
007Methods or devices for eye surgery
008using laser
00861adapted for treatment at a particular location
00868Ciliary muscles or trabecular meshwork
A61F 2009/00891
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
007Methods or devices for eye surgery
008using laser
00885for treating a particular disease
00891Glaucoma
A61F 9/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
007Methods or devices for eye surgery
008using laser
A61F 9/00821
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
007Methods or devices for eye surgery
008using laser
00821for coagulation
Applicants
  • ALEYEGN TECHNOLOGIES LLC [US]/[US]
Inventors
  • DORIN, Giorgio
  • SAMPLES, John
  • BALLARD, Michael K.
  • HEREKAR, Satish
  • EDDINGTON, William
  • BINDER, Perry
Agents
  • MCGRATH, Ethan A.
Priority Data
62/755,29802.11.2018US
62/888,15316.08.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) LASER THERAPY FOR TREATMENT AND PREVENTION OF EYE DISEASES
(FR) THÉRAPIE AU LASER POUR LE TRAITEMENT ET LA PRÉVENTION DE MALADIES OCULAIRES
Abstract
(EN)
An ab externo automated laser treatment system for treating an eye in a subject, includes a non-contact laser source configured to generate a laser beam having at least one wavelength to treat the eye by directing the laser beam from a location spaced from the eye, wherein the at least one wavelength is a near-infrared wavelength in the range of about 0.5-2.2 µm, a laser scanner optically coupled to the non-contact laser source to receive the laser beam from the non-contact laser source and to scan the laser beam relative to the eye, and a processor, and memory including stored computer-readable instructions that, responsive to execution by the processor, cause the laser treatment system to direct the laser beam to a plurality of trans-scleral treatment locations to be irradiated in a predetermined treatment pattern on an external surface of the eye, wherein the trans-scleral treatment locations are 0-4 mm posterior to the corneolimbal junction, and wherein the laser beam is repetitively directed to the same irradiated trans-scleral treatment locations on the surface of the eye, and the trans-scleral treatment locations are irradiated at intervals sufficient to induce protective thermal preconditioning and therapeutic bio-stimulation of one or more of the trabecular meshwork and/or ciliary body without photocoagulation of the tissue of the eye. Trans-pupillary systems, patient interfaces, and methods are also disclosed.
(FR)
La présente invention concerne un système de traitement au laser automatisé ab externo pour traiter l'œil d'un patient, qui comprend une source laser sans contact conçue pour générer un faisceau laser ayant au moins une longueur d'onde pour traiter l'œil en dirigeant le faisceau laser à partir d'un emplacement espacé de l'œil, ladite longueur d'onde étant une longueur d'onde du proche infrarouge dans la plage comprise entre environ 0,5 et 2,2 µm, un dispositif de balayage laser couplé optiquement à la source laser sans contact pour recevoir le faisceau laser en provenance de la source laser sans contact et pour balayer le faisceau laser par rapport à l'œil, et un processeur, et une mémoire comprenant des instructions mémorisées lisibles par ordinateur qui, en réponse à l'exécution par le processeur, amènent le système de traitement au laser à diriger le faisceau laser vers une pluralité d'emplacements de traitement trans-scléral à exposer au rayonnement selon un schéma de traitement prédéfini sur une surface externe de l'œil, les emplacements de traitement trans-scléral étant de 0 à 4 mm à l'arrière de la jonction de la cornée, et le faisceau laser étant dirigé de manière répétitive vers les mêmes emplacements de traitement trans-scléral exposés au rayonnement sur la surface de l'œil, et les emplacements de traitement trans-scléral étant exposés au rayonnement à des intervalles suffisants pour induire un préconditionnement thermique protecteur et une bio-stimulation thérapeutique d'au moins un parmi le réseau trabéculaire et/ou le corps ciliaire sans photocoagulation du tissu de l'œil. L'invention concerne également des systèmes, des interfaces patients et des procédés trans-pupillaires.
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