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1. WO2020093034 - COMBINED FLUORESCENCE AND LASER SPECKLE CONTRAST IMAGING SYSTEM AND APPLICATIONS OF SAME

Publication Number WO/2020/093034
Publication Date 07.05.2020
International Application No. PCT/US2019/059610
International Filing Date 04.11.2019
IPC
A61B 5/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
A61B 34/20 2016.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
34Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A61B 90/00 2016.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/-A61B50/171
G01N 21/64 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
G01N 21/65 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
65Raman scattering
Applicants
  • VANDERBILT UNIVERSITY [US]/[US]
Inventors
  • MANNOH, Emmanuel A.
  • MAHADEVAN-JANSEN, Anita
Agents
  • XIA, Tim Tingkang
Priority Data
62/754,71702.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMBINED FLUORESCENCE AND LASER SPECKLE CONTRAST IMAGING SYSTEM AND APPLICATIONS OF SAME
(FR) SYSTÈME D'IMAGERIE PAR FLUORESCENCE ET D'IMAGERIE PAR CONTRASTE DE GRANULARITÉ LASER COMBINÉES ET SES APPLICATIONS
Abstract
(EN)
A combined auto-fluorescence imaging and laser speckle contrast imaging (LSCI) system to enable intra-operative parathyroid identification and viability assessment with the same tool. The system includes a light source for emitting a beam of light to illuminate a target of interest, and an imaging head positioned over the target of interest for individually acquiring auto-fluorescence images and LSCI images of light from the illuminated target of interest responsive to the illumination. Auto-fluorescence imaging helps identify the parathyroid, while LSCI helps assess its viability.
(FR)
L'invention concerne un système d'imagerie par auto-fluorescence et d'imagerie par contraste de granularité laser (LSCI) combinées permettant une identification de parathyroïde intra-opératoire et une évaluation de viabilité au moyen du même outil. Le système comprend une source de lumière servant à émettre un faisceau de lumière pour éclairer une cible d'intérêt, et une tête d'imagerie positionnée sur la cible d'intérêt servant à acquérir individuellement des images d'auto-fluorescence et des images de LSCI de lumière provenant de la cible d'intérêt éclairée en réponse à l'éclairement. L'imagerie par auto-fluorescence aide à identifier la parathyroïde, tandis que la LSCI aide à en évaluer la viabilité.
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