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1. WO2020092755 - PACKED INCOMPRESSIBLE CHROMATOGRAPHY RESINS AND METHODS OF MAKING THE SAME

Publication Number WO/2020/092755
Publication Date 07.05.2020
International Application No. PCT/US2019/059141
International Filing Date 31.10.2019
IPC
B01D 15/22 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
08Selective adsorption, e.g. chromatography
10characterised by constructional or operational features
22relating to the construction of the column
CPC
B01D 15/206
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
10characterised by constructional or operational features
20relating to the conditioning of the sorbent material
206Packing or coating
B01D 15/22
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
10characterised by constructional or operational features
22relating to the construction of the column
B01J 20/285
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
281Sorbents specially adapted for preparative, analytical or investigative chromatography
282Porous sorbents
285based on polymers
Applicants
  • REPLIGEN CORPORATION [US]/[US]
Inventors
  • PEYSER, James Ronald
  • CHAN, Alan Kit Ho
Agents
  • KAUSHAL, Dhruv
Priority Data
62/753,60431.10.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PACKED INCOMPRESSIBLE CHROMATOGRAPHY RESINS AND METHODS OF MAKING THE SAME
(FR) RÉSINES DE CHROMATOGRAPHIE INCOMPRESSIBLES EMBALLÉES ET LEURS PROCÉDÉS DE FABRICATION
Abstract
(EN)
This disclosure provides chromatography columns that are packed with incompressible media such as ceramic hydroxyapatite particles, which exhibit high separation performance that is robust to transportation and multiple uses. The columns can be made by applying axial compression using rigid bodies, such as porous frits and/or flow regulators.
(FR)
La présente invention concerne des colonnes de chromatographie qui sont emballées avec des supports incompressibles tels que des particules d'hydroxyapatite céramique, qui ont une haute performance de séparation robuste des points de vue transport et utilisations multiples. Les colonnes peuvent être fabriquées par application d'une compression axiale à l'aide de corps rigides, tels que des frittes poreuses et/ou des régulateurs d'écoulement.
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