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1. WO2020092654 - ANTI-CD45 ANTIBODIES AND CONJUGATES THEREOF

Publication Number WO/2020/092654
Publication Date 07.05.2020
International Application No. PCT/US2019/058971
International Filing Date 30.10.2019
IPC
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C07K 16/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
Applicants
  • MAGENTA THERAPEUTICS, INC. [US]/[US]
Inventors
  • PALCHAUDHURI, Rahul
  • PEARSE, Bradley R.
  • ADAMS, Hillary
  • MCDONOUGH, Sean
  • COOKE, Michael
  • BOITANO, Anthony
Agents
  • COWLES, Cristin H.
Priority Data
62/753,00230.10.2018US
62/774,00630.11.2018US
62/807,58219.02.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-CD45 ANTIBODIES AND CONJUGATES THEREOF
(FR) ANTICORPS ANTI-CD45 ET LEURS CONJUGUÉS
Abstract
(EN)
Disclosed are anti-CD45 antibodies and antibody drug conjugates (ADCs) useful in therapeutic methods, including targeting CD45 expressing hematopoietic stem cells (HSCs) or immune cells prior to transplantation.
(FR)
L'invention concerne des anticorps anti-CD45 et des conjugués anticorps-médicament (ADC) utiles dans des procédés thérapeutiques, comprenant le ciblage de CD45 exprimant des cellules souches hématopoïétiques (HSC) ou des cellules immunitaires avant une transplantation.
Latest bibliographic data on file with the International Bureau