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1. WO2020092314 - COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CDK9 ACTIVITY

Publication Number WO/2020/092314
Publication Date 07.05.2020
International Application No. PCT/US2019/058482
International Filing Date 29.10.2019
Chapter 2 Demand Filed 06.02.2020
IPC
C07D 487/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/519 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • KRONOS BIO, INC. [US]/[US]
Inventors
  • MIKOCHIK, Peter
  • VACCA, Joseph
  • FREEMAN, David
  • TASKER, Andrew
Agents
  • HENSCHEL, Rouget F.
Priority Data
62/752,63530.10.2018US
62/884,99309.08.2019US
62/910,05803.10.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CDK9 ACTIVITY
(FR) COMPOSÉS, COMPOSITIONS ET PROCÉDÉS DE MODULATION DE L'ACTIVITÉ DE CDK9
Abstract
(EN)
Inhibitors of CDK9 that are pyrazolo [1,5-α] pyrimidine derivatives and salts thereof, corresponding to formula (I): (I).
(FR)
L'invention concerne des inhibiteurs de CDK9 qui sont des dérivés de pyrazolo [1,5-alpha] pyrimidine et des sels de ceux-ci, correspondant à la formule (I) : (I)
Latest bibliographic data on file with the International Bureau