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1. WO2020092277 - DNA DATA STORAGE ON TWO-DIMENSIONAL SUPPORT MATERIAL

Publication Number WO/2020/092277
Publication Date 07.05.2020
International Application No. PCT/US2019/058414
International Filing Date 29.10.2019
IPC
C12Q 1/6806 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction assay
CPC
B01J 19/0046
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
B82Y 15/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
15Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
B82Y 30/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
30Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
40Manufacture or treatment of nanostructures
C12N 15/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
C12N 15/1006
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
10Processes for the isolation, preparation or purification of DNA or RNA
1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
1006by means of a solid support carrier, e.g. particles, polymers
Applicants
  • MICROSOFT TECHNOLOGY LICENSING, LLC [US]/[US]
Inventors
  • STRAUSS, Karin
  • NGUYEN, Bichlien Hoang
  • GRASS, Robert N.
  • KOHLL, Alexander Xavier Christof
  • CHEN, Weida
Agents
  • MINHAS, Sandip S.
  • ADJEMIAN, Monica
  • BARKER, Doug
  • CHATTERJEE, Aaron C.
  • CHEN, Wei-Chen Nicholas
  • CHOI, Daniel
  • CHURNA, Timothy
  • DINH, Phong
  • EVANS, Patrick
  • GABRYJELSKI, Henry
  • GOLDSMITH, Micah P.
  • GUPTA, Anand
  • HINOJOSA-SMITH, Brianna L.
  • HWANG, William C.
  • JARDINE, John S.
  • LEE, Sunah
  • LEMMON, Marcus
  • MARQUIS, Thomas
  • MEYERS, Jessica
  • ROPER, Brandon
  • SPELLMAN, Steven
  • SULLIVAN, Kevin
  • SWAIN, Cassandra T.
  • TABOR, Ben
  • WALKER, Matt
  • WIGHT, Stephen A.
  • WISDOM, Gregg
  • WONG, Ellen
  • WONG, Thomas S.
  • ZHANG, Hannah
  • TRAN, Kimberly
Priority Data
16/179,33002.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DNA DATA STORAGE ON TWO-DIMENSIONAL SUPPORT MATERIAL
(FR) STOCKAGE DE DONNÉES D'ADN SUR UN MATÉRIAU DE SUPPORT BIDIMENSIONNEL
Abstract
(EN)
A data storage medium is disclosed comprising a two-dimensional (2D) support structure onto which artificially synthesized DNA molecules encoding digital information are placed and then covered with a protective layer. The 2D support structure is formed from a material such as metal foil, glass, or plastic. The 2D support structure may be functionalized with positively charged molecules to improve DNA adhesion. The DNA is protected from degradation by encapsulation in a protective layer of a non-reactive material such as silica or a thin layer of metal. A process for storing DNA on 2D support structures is also disclosed. Correlation of specific DNA molecules with a physical storage location on a 2D support structure provides geometric addressability for selective access to specific digital information.
(FR)
Support de stockage de données comprenant une structure de support bidimensionnelle (2D) sur laquelle des molécules d'ADN synthétisées artificiellement codant des informations numériques sont placées puis recouvertes d'une couche protectrice. La structure de support 2D est formée à partir d'un matériau tel qu'une feuille métallique, du verre ou du plastique. La structure de support 2D peut être fonctionnalisée avec des molécules chargées positivement pour améliorer l'adhérence de l'ADN. L'ADN Est protégé contre la dégradation par encapsulation dans une couche protectrice d'un matériau non réactif tel que de la silice ou une couche mince de métal. L'Invention concerne en outre un procédé de stockage D'ADN sur des structures de support 2D. La corrélation de molécules d'ADN spécifiques avec un emplacement de stockage physique sur une structure de support 2D fournit une capacité d'adressage géométrique pour un accès sélectif à des informations numériques spécifiques.
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