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1. WO2020092235 - GROUPING NEUROPSYCHOTYPES OF PATIENTS WITH CHRONIC PAIN FOR PERSONALIZED MEDICINE

Publication Number WO/2020/092235
Publication Date 07.05.2020
International Application No. PCT/US2019/058341
International Filing Date 28.10.2019
IPC
A61B 5/055 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
05Measuring for diagnosis by means of electric currents or magnetic fields
055involving electronic or nuclear magnetic resonance, e.g. magnetic resonance imaging
G06Q 50/22 2018.01
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
QDATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES, NOT OTHERWISE PROVIDED FOR
50Systems or methods specially adapted for specific business sectors, e.g. utilities or tourism
10Services
22Social work
G16H 20/00 2018.01
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
20ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
G16H 30/00 2018.01
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
30ICT specially adapted for the handling or processing of medical images
Applicants
  • NORTHWESTERN UNIVERSITY [US]/[US]
Inventors
  • APKARIAN, Apkar Vania
  • VACHON-PRESSEAU, Etienne
  • BERGER, Sara E.
  • SCHNITZER, Thomas J.
Agents
  • RICHEY, Samuel P.
  • PATEL, Binal J.
Priority Data
62/751,77829.10.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GROUPING NEUROPSYCHOTYPES OF PATIENTS WITH CHRONIC PAIN FOR PERSONALIZED MEDICINE
(FR) REGROUPEMENT DE NEUROPSYCHOTYPES DE PATIENTS ATTEINTS DE DOULEUR CHRONIQUE POUR UN MÉDICAMENT PERSONNALISÉ
Abstract
(EN)
Systems as described herein can include diagnosing and treating patients with chronic conditions, such as chronic back pain. A transition to chronic pain can include brain adaptations that can carve the state of chronic pain. Additionally, pain characteristics, pain related disability, and responses to treatment can be at least partially determined by psychological factors and/or personality properties. Patients can be classified into a plurality (e.g., five) neuropsychotypes based on set of brain imaging data and psychological assessment. Once classified, personalized treatment options can be developed for chronic pain patients. However, it should be noted that any of a variety of patients with any of a variety of chronic disorders such as, but not limited to, chronic negative mood disorders, such as PTSD, depression, and anxiety, can be diagnosed and treated using any of the systems and processes described herein.
(FR)
L'invention concerne des systèmes qui peuvent comprendre le diagnostic et le traitement de patients présentant des états chroniques, tels qu'un mal de dos chronique. Une transition vers la douleur chronique peut comprendre des adaptations cérébrales qui peuvent entraîner l'état de douleur chronique. De plus, des caractéristiques de douleur, un handicap lié à la douleur et des réponses au traitement peuvent être au moins partiellement déterminées par des facteurs psychologiques et/ou des propriétés de personnalité. Les patients peuvent être classés en une pluralité (par exemple cinq) neuropsychotypes sur la base d'un ensemble de données d'imagerie cérébrale et d'une évaluation psychologique. Une fois la classification effectuée, des options de traitement personnalisées peuvent être mises au point pour des patients souffrant d'une douleur chronique. Il convient cependant de noter que l'un quelconque d'une variété de patients souffrant d'une variété de troubles chroniques tels que, sans exhaustivité, des troubles de l'humeur négative chronique, tels qu'un trouble de stress post-traumatique, la dépression et l'anxiété, peuvent être diagnostiqués et traités à l'aide de l'un quelconque des systèmes et procédés selon la présente invention.
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