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1. WO2020091866 - PARTICLE SORTING MODULE WITH ALIGNMENT WINDOW, SYSTEMS AND METHODS OF USE THEREOF

Publication Number WO/2020/091866
Publication Date 07.05.2020
International Application No. PCT/US2019/044215
International Filing Date 30.07.2019
IPC
G01N 15/14 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation
G01N 33/49 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
49blood
CPC
G01N 15/1434
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation, e.g. flow cytometers
1434using an analyser being characterised by its optical arrangement
G01N 2015/1481
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation, e.g. flow cytometers
1481Optical analysis of particle in droplet
G01N 2015/149
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation, e.g. flow cytometers
149Sorting the particles
Applicants
  • BECTON, DICKINSON AND COMPANY [US]/[US]
  • DEMBSKI, Kyle [US]/[US]
  • LANKILA, Henry [US]/[US]
Inventors
  • DEMBSKI, Kyle
  • LANKILA, Henry
Agents
  • FIELD, Bret E.
Priority Data
62/752,79330.10.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PARTICLE SORTING MODULE WITH ALIGNMENT WINDOW, SYSTEMS AND METHODS OF USE THEREOF
(FR) MODULE DE TRI DE PARTICULES À FENÊTRE D'ALIGNEMENT, SYSTÈMES ET PROCÉDÉS D'UTILISATION DE CE DERNIER
Abstract
(EN)
Aspects of the present disclosure include a particle sorting module having an opening that is configured for visualizing droplets of a deflected flow stream. Particle sorting modules according to certain embodiments include a housing having a proximal end, a distal end and a wall therebetween having an opening positioned in the wall that is configured for aligning the flow stream with one or more sample containers at the distal end. Systems and methods for aligning a flow stream with one or more sample containers and sorting particles of a sample (e.g., a biological sample) are also provided. Kits having one or more of the particle sorting modules suitable for coupling with a particle sorting system and for practicing the subject methods are also described.
(FR)
Des aspects de la présente invention comprennent un module de tri de particules comprenant une ouverture configurée pour visualiser des gouttelettes d'un flux d'écoulement dévié. Selon certains modes de réalisation, des modules de tri de particules comprennent un boîtier comprenant une extrémité proximale, une extrémité distale et une paroi entre ces dernières possédant une ouverture positionnée dans la paroi configurée pour aligner le flux d'écoulement avec un ou plusieurs récipients d'échantillon au niveau de l'extrémité distale. L'invention concerne également des systèmes et des procédés permettant d'aligner un flux d'écoulement avec un ou plusieurs récipients d'échantillon et de trier des particules d'un échantillon (par exemple, un échantillon biologique). L'invention concerne également des kits comprenant un ou plusieurs modules des modules de tri de particules permettant un accouplement avec un système de tri de particules et une mise en œuvre des procédés de l'invention.
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