Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020091232 - COMPOSITION FOR PREVENTION, IMPROVEMENT OR TREATMENT OF ATOPIC DERMATITIS, COMPRISING LUMBRICUS RUBELLUS EXTRACT OR FRACTION THEREOF AS ACTIVE INGREDIENT

Publication Number WO/2020/091232
Publication Date 07.05.2020
International Application No. PCT/KR2019/012511
International Filing Date 26.09.2019
IPC
A23L 33/105 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A61K 35/62 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
56Materials from animals other than mammals
62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61P 17/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61K 8/98 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
96containing materials, or derivatives thereof, of undetermined constitution
98of animal origin
A61Q 19/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
Applicants
  • 한국 한의학 연구원 KOREA INSTITUTE OF ORIENTAL MEDICINE [KR]/[KR]
Inventors
  • 김동선 KIM, Dong Seon
  • 이윤미 LEE, Yun Mi
  • 김태인 KIM, Tae In
  • 성윤영 SUNG, Yoon-Young
  • 손은정 SON, Eun Jung
  • 이영실 LEE, Young-Sil
  • 육흥주 YUK, Heung Joo
Agents
  • 최규환 CHOI, Kyu Whan
Priority Data
10-2018-013050630.10.2018KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) COMPOSITION FOR PREVENTION, IMPROVEMENT OR TREATMENT OF ATOPIC DERMATITIS, COMPRISING LUMBRICUS RUBELLUS EXTRACT OR FRACTION THEREOF AS ACTIVE INGREDIENT
(FR) COMPOSITION POUR LA PRÉVENTION, L’AMÉLIORATION OU LE TRAITEMENT DE LA DERMATITE ATOPIQUE COMPRENANT UN EXTRAIT DE LUMBRICUS RUBELLUS OU UNE FRACTION DE CELUI-CI EN TANT QUE PRINCIPE ACTIF
(KO) 구인 추출물 또는 이의 분획물을 유효성분으로 포함하는 아토피 피부염의 예방, 개선 또는 치료용 조성물
Abstract
(EN)
The present invention relates to a composition for prevention, improvement or treatment of atopic dermatitis, comprising a Lumbricus rubellus extract as an active ingredient, wherein the Lumbricus rubellus extract and a fraction thereof are not cytotoxic, reduce production of NO, as well as reduce production of inflammation-induced chemokine RANTES with increased secretion from human skin keratinocytes (HaCaT cell) by TNF-a and IFN-γ, and therefore can be utilized as a composition for preventing or treating various inflammatory diseases.
(FR)
La présente invention concerne une composition pour la prévention, l'amélioration ou le traitement de la dermatite atopique, comprenant un extrait de Lumbricus rubellus en tant que principe actif, l'extrait de Lumbricus rubellus et une fraction de celui-ci n'étant pas cytotoxiques, réduisant la production de NO, et réduisant également la production de la chimiokine induite par l'inflammation RANTES avec une sécrétion accrue de kératinocytes cutanés humains (cellule HaCaT) par TNF-a et IFN-γ, et peut donc être utilisée en tant que composition pour prévenir ou traiter diverses maladies inflammatoires.
(KO)
본 발명은 구인 추출물을 유효성분으로 포함하는 아토피 피부염의 예방, 개선 또는 치료용 조성물에 관한 것으로, 구인 추출물 및 이의 분획물은 세포독성이 없으며, NO 생성량을 감소시킬 뿐만 아니라, TNF-a와 IFN-γ에 의해 인간피부각질세포(HaCaT cell)로부터 분비가 증가된 염증 유발 케모카인 RANTES의 생성량을 감소시키므로, 다양한 염증성 질환의 예방 또는 치료용 조성물로 유용하게 사용될 수 있다.
Latest bibliographic data on file with the International Bureau