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1. WO2020091054 - 1,4-DIAZOCANE COMPOUND OR SALT THEREOF

Publication Number WO/2020/091054
Publication Date 07.05.2020
International Application No. PCT/JP2019/043068
International Filing Date 01.11.2019
IPC
C07C 311/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
311Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
16having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
18to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
C07D 245/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
245Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
02not condensed with other rings
C07D 401/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants
  • 株式会社デ・ウエスタン・セラピテクス研究所 D. WESTERN THERAPEUTICS INSTITUTE, INC. [JP]/[JP]
  • わかもと製薬株式会社 WAKAMOTO PHARMACEUTICAL CO., LTD. [JP]/[JP]
Inventors
  • 鷲見 賢吾 SUMI, Kengo
  • 小出 智之 KOIDE, Tomoyuki
  • 木全 脩 KIMATA, Osamu
  • 高島 有史 TAKASHIMA, Yuji
  • 増渕 一直 MASUBUCHI, Kazunao
Agents
  • 特許業務法人アルガ特許事務所 THE PATENT CORPORATE BODY ARUGA PATENT OFFICE
Priority Data
2018-20694101.11.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) 1,4-DIAZOCANE COMPOUND OR SALT THEREOF
(FR) COMPOSÉ DE 1,4-DIAZOCANE OU SEL DE CELUI-CI
(JA) 1,4-ジアゾカン化合物又はその塩
Abstract
(EN)
The invention provides a novel production method for an isoquinoline-6-sulfonamide derivative that is useful as a medicinal drug, and also provides an intermediate for use in the method. The invention is the 1,4-diazocane compound represented by general formula (A), or a salt thereof (in the formula, R4 represents an amino-protecting group).
(FR)
L'invention concerne un nouveau procédé de production d'un dérivé d'isoquinoléine-6-sulfonamide qui est utile en tant que médicament médicinal, et concerne également un intermédiaire destiné à être utilisé dans le procédé. L'invention concerne le composé de 1,4-diazocane représenté par la formule générale (A), ou un sel de celui-ci (dans la formule, R4 représente un groupe protecteur amino).
(JA)
医薬として有用なイソキノリン-6-スルホンアミド誘導体の新規製造法及びそれに用いる中間体の提供。 一般式(A)(式中、R4はアミノ保護基を示す) で表される1,4-ジアゾカン化合物又はその塩。
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