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1. WO2020089828 - AN IMPROVED PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATES

Publication Number WO/2020/089828
Publication Date 07.05.2020
International Application No. PCT/IB2019/059349
International Filing Date 31.10.2019
IPC
C07D 487/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/4985 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
Applicants
  • STEREOKEM PVT. LTD. [IN]/[IN]
  • JANAGANI, Satyanarayana [IN]/[IN] (US)
  • THADURI, Venkateshwar Kumar [IN]/[IN] (US)
  • BANDI, Venugopala Rao [IN]/[IN] (US)
  • VAMARAJU, Ravisankar [IN]/[IN] (US)
Inventors
  • JANAGANI, Satyanarayana
  • THADURI, Venkateshwar Kumar
  • BANDI, Venugopala Rao
  • VAMARAJU, Ravisankar
Agents
  • SURAPUREDDY, Padmaja
Priority Data
20184104132401.11.2018IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) AN IMPROVED PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATES
(FR) PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION DE SITAGLIPTINE ET DE SES INTERMÉDIAIRES
Abstract
(EN)
The present invention relates to a process for the preparation of novel intermediates useful for the preparation of Sitagliptin or its pharmaceutically acceptable salts. The present invention relates to an efficient process for the preparation of Sitagliptin intermediates. The present invention relates to an improved process for the preparation of Sitagliptin or its pharmaceutically acceptable salts.
(FR)
La présente invention concerne un procédé de préparation de nouveaux intermédiaires utiles pour la préparation de sitagliptine ou de ses sels pharmaceutiquement acceptables. La présente invention concerne un procédé efficace pour la préparation d'intermédiaires de sitagliptine. La présente invention concerne également un procédé amélioré pour la préparation de sitagliptine ou de ses sels pharmaceutiquement acceptables.
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