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1. WO2020089561 - USE OF AN EGG GRAFTED WITH TUMOR CELLS IN ORDER TO STUDY THE ANTI-CANCER EFFECTIVENESS OF IMMUNE THERAPIES IN THE ABSENCE OF IMMUNE EFFECTOR CELLS OTHER THAN THOSE IN THE GRAFTED EGG

Publication Number WO/2020/089561
Publication Date 07.05.2020
International Application No. PCT/FR2019/052572
International Filing Date 29.10.2019
IPC
C12N 5/09 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
09Tumour cells
A01K 67/027 2006.01
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
CPC
A01K 2207/12
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2207Modified animals
12Animals modified by administration of exogenous cells
A01K 2227/30
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2227Animals characterised by species
30Bird
A01K 2267/0331
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
2267Animals characterised by purpose
03Animal model, e.g. for test or diseases
0331Animal model for proliferative diseases
A01K 67/0271
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67Rearing or breeding animals, not otherwise provided for; New breeds of animals
027New breeds of vertebrates
0271Chimeric animals, e.g. comprising exogenous cells
C12N 2503/02
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2503Use of cells in diagnostics
02Drug screening
C12N 5/0693
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0693Tumour cells; Cancer cells
Applicants
  • INOVOTION [FR]/[FR]
Inventors
  • ROUSSET, Xavier
  • DOSDA, Emilien
  • VIALLET, Jean
Agents
  • REGIMBEAU
Priority Data
186000029.10.2018FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) USE OF AN EGG GRAFTED WITH TUMOR CELLS IN ORDER TO STUDY THE ANTI-CANCER EFFECTIVENESS OF IMMUNE THERAPIES IN THE ABSENCE OF IMMUNE EFFECTOR CELLS OTHER THAN THOSE IN THE GRAFTED EGG
(FR) UTILISATION D'UN OEUF GREFFE AVEC DES CELLULES TUMORALES POUR ETUDIER L'EFFICACITE ANTI-CANCEREUSE D'IMMUNOTHERAPIES, EN L'ABSENCE DE CELLULES EFFECTRICES IMMUNITAIRES AUTRES QUE CELLES DE L'OEUF GREFFE
Abstract
(EN)
The invention relates to the use of an embryonated egg model grafted with tumor cells to study the anti-cancer effectiveness or screen immunotherapeutic molecules in the absence of immune effector cells other than those in the grafted egg.
(FR)
La présente invention concerne l'utilisation d'un modèle d'œuf embryonné greffé avec des cellules tumorales pour étudier l'efficacité anti-cancéreuse ou cribler des molécules immunothérapeutiques, en l'absence de cellules effectrices immunitaires autres que celles de l'œuf greffé.
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