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1. WO2020087896 - MEDICAL DEGRADABLE POLYURETHANE HAVING ANTIBACTERIAL ACTIVITY AND APPLICATION THEREOF

Publication Number WO/2020/087896
Publication Date 07.05.2020
International Application No. PCT/CN2019/084743
International Filing Date 28.04.2019
IPC
C08G 18/64 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
18Polymeric products of isocyanates or isothiocyanates
06with compounds having active hydrogen
28characterised by the compounds used containing active hydrogen
40High-molecular-weight compounds
64Macromolecular compounds not provided for by groups C08G18/42-C08G18/63104
C08G 18/42 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
18Polymeric products of isocyanates or isothiocyanates
06with compounds having active hydrogen
28characterised by the compounds used containing active hydrogen
40High-molecular-weight compounds
42Polycondensates having carboxylic or carbonic ester groups in the main chain
A61K 49/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
04X-ray contrast preparations
A61K 9/50 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
A61K 47/34 2017.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Applicants
  • 珠海睿展生物材料有限公司 ZHUHAI RUIZHAN BIO-MATERIAL CO., LTD [CN]/[CN]
Inventors
  • 张文芳 ZHANG, Wenfang
Agents
  • 北京科亿知识产权代理事务所(普通合伙) BEIJING KEYI INTELLECTUAL PROPERTY FIRM
Priority Data
201811263478.828.10.2018CN
201910270022.204.04.2019CN
201910270521.104.04.2019CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) MEDICAL DEGRADABLE POLYURETHANE HAVING ANTIBACTERIAL ACTIVITY AND APPLICATION THEREOF
(FR) POLYURÉTHANE DÉGRADABLE MÉDICAL AYANT UNE ACTIVITÉ ANTIBACTÉRIENNE ET SON APPLICATION
(ZH) 一种具有抗菌活性的医用可降解聚氨酯及其用途
Abstract
(EN)
Disclosed in the present invention are a medical degradable polyurethane having antibacterial activity and an application thereof, particularly, a medical degradable polyurethane containing chitosan or a derivative thereof, a preparation method for the polyurethane, and an application of the polyurethane in implant biological material. Medical degradable polyurethanes having antibacterial activity, different molecular weights and degradation properties can be designed and synthesized according to the requirements of regenerative medicine and medical devices implanted in the body.
(FR)
La présente invention concerne un polyuréthane dégradable médical ayant une activité antibactérienne et une application de celui-ci, notamment un polyuréthane dégradable médical contenant du chitosane ou un dérivé de celui-ci, un procédé de préparation du polyuréthane et une application du polyuréthane dans un matériau biologique d'implant. Des polyuréthanes dégradables médicaux ayant une activité antibactérienne, différents poids moléculaires et propriétés de dégradation peuvent être conçus et synthétisés selon les exigences de la médecine régénérative et des dispositifs médicaux implantés dans le corps.
(ZH)
本发明公开了一种具有抗菌活性的医用可降解聚氨酯及其用途,具体涉及一种含有壳聚糖或其衍生物作的医用可降解聚氨酯、其制备方法和在植介入生物材料方面的应用,可以根据再生医学以及植入体内的医疗器械的需要,设计合成不同分子量和降解性能的具有抗菌活性的医用可降解聚氨酯。
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