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1. WO2020087822 - TRYPSIN-RESISTANT ANTIMICROBIAL AGENT

Publication Number WO/2020/087822
Publication Date 07.05.2020
International Application No. PCT/CN2019/076716
International Filing Date 01.03.2019
IPC
C07K 14/245 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
24from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
245Escherichia (G)
C12P 21/02 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21Preparation of peptides or proteins
02having a known sequence of two or more amino acids, e.g. glutathione
C12R 1/19 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1Microorganisms
01Bacteria or actinomycetales
185Escherichia
19Escherichia coli
CPC
C07K 14/245
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
24from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
245Escherichia (G)
Applicants
  • 中国农业大学 CHINA AGRICULTURAL UNIVERSITY [CN]/[CN]
Inventors
  • 谯仕彦 QIAO, Shiyan
Agents
  • 北京迎硕知识产权代理事务所(普通合伙) BEIJING YINGTUO INTELLECTUAL PROPERTY LAWFIRM
Priority Data
201811274568.730.10.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) TRYPSIN-RESISTANT ANTIMICROBIAL AGENT
(FR) AGENT ANTIMICROBIEN RÉSISTANT À LA TRYPSINE
(ZH) 一种耐受胰蛋白酶的抗菌肽
Abstract
(EN)
Provided is a trypsin-resistant antimicrobial agent, which is a mutant of MccC7, said mutant being R2A, R2H, R2L, R2T, R2Q, and R2K, wherein R2A, R2H, R2T and R2Q can resist to trypsin.
(FR)
L’invention concerne un agent microbien résistant à la trypsine, lequel est un mutant de MccC7, ledit mutant désignant R2A, R2H, R2L, R2T, R2Q et R2K, et étant charactérisé en ce que R2A, R2H, R2T et R2Q peuvent résister à la trypsine.
(ZH)
提供一种耐受胰蛋白酶的抗菌肽,所述抗菌肽为MccC7的突变体,所述突变体为R2A、R2H、R2L、R2T、R2Q和R2K;其中,所述R2A、R2H、R2T和R2Q能耐受胰蛋白酶。
Also published as
Latest bibliographic data on file with the International Bureau