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1. WO2020087765 - LONG-ACTING ANTIBACTERIAL BAND-AID

Publication Number WO/2020/087765
Publication Date 07.05.2020
International Application No. PCT/CN2019/000112
International Filing Date 27.05.2019
IPC
A61L 15/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
42Use of materials characterised by their function or physical properties
44Medicaments
A61L 15/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
22containing macromolecular materials
28Polysaccharides or their derivatives
CPC
A61L 15/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
22containing macromolecular materials
28Polysaccharides or their derivatives
A61L 15/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
42Use of materials characterised by their function or physical properties
44Medicaments
A61L 2300/204
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
20containing or releasing organic materials
204with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
Applicants
  • 广东药科大学 GUANG DONG PHARMACEUTICAL UNIVERSITY [CN]/[CN]
Inventors
  • 曹华 CAO, Hua
  • 郭鹏峰 GUO, Pengfeng
  • 徐晓琳 XU, Xiaolin
Common Representative
  • 广东药科大学 GUANG DONG PHARMACEUTICAL UNIVERSITY
Priority Data
201811298085.002.11.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) LONG-ACTING ANTIBACTERIAL BAND-AID
(FR) PANSEMENT ANTIBACTÉRIEN À ACTION PROLONGÉE
(ZH) 一种长效抑菌创可贴
Abstract
(EN)
A long-acting antibacterial band-aid, comprising an adhesive tape layer (1), a sponge layer (3) composed of chitosan and cellulose, and a porous drug layer composed of 6,6'-difluoro-3,3'-biimidazo[1,2-a]pyridine and 5-hexanoyl-2-methyl-N-o-tolyl-3-carboxamide, the sponge layer (3) being located between the adhesive tape layer (1) and the porous drug layer (2). The band-aid comprises a porous drug layer (2), and the contained drugs may effectively inhibit the proliferation of bacteria, while blood and tissue fluid at a wound may enter the sponge layer (2) by means of small pores while the drugs are released; meanwhile, the sponge layer (2) may quickly absorb blood and tissue fluid, has an antibacterial effect, may better maintain a sterile environment, and promotes the healing of a wound.
(FR)
L'invention concerne un pansement antibactérien à action prolongée, comprenant une couche de ruban adhésif (1), une couche d'éponge (3) composée de chitosane et de cellulose, et une couche poreuse de médicament composée de 6,6'-difluoro-3,3'-biimidazo[1,2-a]pyridine et de 5-hexanoyl-2-methyl-N-o-tolyl-3-carboxamide, la couche d'éponge (3) étant située entre la couche de ruban adhésif (1) et la couche poreuse de médicament (2). Le pansement comprend une couche poreuse de médicament (2), et les médicaments contenus peuvent inhiber efficacement la prolifération de bactéries, tandis que le sang et le fluide tissulaire d'une plaie peuvent pénétrer dans la couche d'éponge (2) par de petits pores tandis que les médicaments sont libérés ; pendant ce temps, la couche d'éponge (2) peut absorber rapidement le sang et le fluide tissulaire, a un effet antibactérien, peut maintenir plus efficacement un environnement stérile et favorise la cicatrisation d'une plaie.
(ZH)
一种长效抑菌创可贴,包括胶布层(1)、壳聚糖和纤维素组成的海绵层(3)、6,6'-二氟-3,3'-联咪唑并[1,2-a]吡啶和5-己酰基-2-甲基-N-邻甲苯基-3-甲酰胺组成的多孔药物层(2),海绵层(3)位于胶布层(1)和多孔药物层(2)之间。创可贴含有多孔药物层(2),所含药物能有效抑制细菌增殖,且能在释放药物的同时使血液及伤口处组织液通过小孔进入到海绵层(2),同时海绵层(2)能迅速吸收血液和组织液,具有抑菌效果,能更好的维持无菌环境,促进伤口愈合。
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