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1. WO2020072491 - BREVICAN-BINDING PEPTIDES FOR BRAIN TUMOR IMAGING

Publication Number WO/2020/072491
Publication Date 09.04.2020
International Application No. PCT/US2019/054064
International Filing Date 01.10.2019
IPC
A61K 38/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
A61K 38/08 2019.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/30 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
CPC
A61K 38/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
A61K 38/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
08Peptides having 5 to 11 amino acids
Applicants
  • THE BRIGHAM AND WOMEN'S HOSPITAL, INC. [US]/[US]
Inventors
  • CHO, Choi-Fong
  • LAWLER, Sean Edward
  • VIAPIANO, Mariano Sebastian
Agents
  • DEYOUNG, Janice Kugler
  • FASSE, J. Peter
Priority Data
62/739,84501.10.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BREVICAN-BINDING PEPTIDES FOR BRAIN TUMOR IMAGING
(FR) PEPTIDES DE LIAISON AU BRÉVICAN POUR L'IMAGERIE D'UNE TUMEUR CÉRÉBRALE
Abstract
(EN)
Compositions comprising peptides that bind specifically to BΔg (deglycosylated brevican), and methods of use thereof to deliver therapeutic and diagnostic agents to brevican-expressing cells, e.g., cancerous cells, e.g., brain cancer cells, e.g., glioblastoma cells.
(FR)
L'invention concerne des compositions comprenant des peptides qui se lient spécifiquement au BΔg (brévican déglycosylé) et leurs méthodes d'utilisation pour administrer des agents thérapeutiques et diagnostiques à des cellules exprimant le brévican, par exemple des cellules cancéreuses, par exemple des cellules cancéreuses du cerveau, par exemple des cellules de glioblastomes.
Latest bibliographic data on file with the International Bureau