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1. WO2020072478 - DELIVERY OF LOW SURFACE TENSION COMPOSITIONS TO THE PULMONARY SYSTEM VIA ELECTRONIC BREATH ACTUATED DROPLET DELIVERY DEVICE

Publication Number WO/2020/072478
Publication Date 09.04.2020
International Application No. PCT/US2019/054042
International Filing Date 01.10.2019
IPC
B05B 17/06 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
05SPRAYING OR ATOMISING IN GENERAL; APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL
BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
17Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass
04operating with special methods
06using ultrasonic vibrations
A61M 15/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15Inhalators
CPC
A61B 5/4833
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
48Other medical applications
4833Assessment of subject's compliance to treatment
A61M 11/001
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
11Sprayers or atomisers specially adapted for therapeutic purposes
001Particle size control
A61M 15/0026
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
15Inhalators
0001Details of inhalators; Constructional features thereof
0021Mouthpieces therefor
0025with caps
0026Hinged caps
A61M 15/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
15Inhalators
0065Inhalators with dosage or measuring devices
0068Indicating or counting the number of dispensed doses or of remaining doses
008Electronic counters
A61M 15/0081
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
15Inhalators
0065Inhalators with dosage or measuring devices
0068Indicating or counting the number of dispensed doses or of remaining doses
0081Locking means
A61M 15/0085
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
15Inhalators
0085using ultrasonics
Applicants
  • PNEUMA RESPIRATORY, INC. [US]/[US]
Inventors
  • HUNTER, Charles Eric
  • THOMAS, Brian H.
  • HEBRANK, John H.
Agents
  • VINNOLA, Milan M.
  • D'AGOSTIN, Rhiannon I.
  • ELLIOTT, Taryn A.
  • WORRALL, Timothy A.
  • HANSON, Roberta J.
  • VU, Stephanie T.
Priority Data
62/739,74001.10.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DELIVERY OF LOW SURFACE TENSION COMPOSITIONS TO THE PULMONARY SYSTEM VIA ELECTRONIC BREATH ACTUATED DROPLET DELIVERY DEVICE
(FR) ADMINISTRATION DE COMPOSITIONS À FAIBLE TENSION DE SURFACE AU SYSTÈME PULMONAIRE PAR L'INTERMÉDIAIRE D'UN DISPOSITIF ÉLECTRONIQUE DE DISTRIBUTION DE GOUTTELETTES ACTIONNÉ PAR LA RESPIRATION
Abstract
(EN)
A droplet delivery device and related methods for delivering a low surface tension composition as a stream of droplets to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, an ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The ejector mechanism includes a piezoelectric actuator and an aperture plate, the aperture plate having a plurality of openings formed through its thickness, and one or more surfaces configured to provide a desired surface contact angle, and the piezoelectric actuator operable to oscillate the aperture plate at a frequency to thereby generate the ejected stream of droplets.
(FR)
L'invention concerne un dispositif d'administration de gouttelettes et des méthodes associées permettant d'administrer une composition à faible tension de surface sous la forme d'un flux de gouttelettes à un sujet pour une utilisation pulmonaire. Le dispositif d'administration de gouttelettes comprend un boîtier, un réservoir et un mécanisme éjecteur, et au moins un capteur de pression différentielle. Le dispositif d'administration de gouttelettes est actionné automatiquement par la respiration de l'utilisateur lorsque le capteur de pression différentielle détecte une variation de pression prédéfinie à l'intérieur du boîtier. Le mécanisme éjecteur comprend un actionneur piézoélectrique et une plaque d'ouverture, la plaque d'ouverture ayant une pluralité d'ouvertures formées à travers son épaisseur, et une ou plusieurs surfaces configurées pour fournir un angle de contact superficiel souhaité, et l'actionneur piézoélectrique pouvant fonctionner pour faire osciller la plaque d'ouverture à une fréquence pour ainsi générer le flux éjecté de gouttelettes.
Latest bibliographic data on file with the International Bureau