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1. WO2020071912 - EXTENDED RELEASE FORMULATIONS OF HUMAN CHORIONIC GONADOTROPIN (HCG)

Publication Number WO/2020/071912
Publication Date 09.04.2020
International Application No. PCT/NL2019/050660
International Filing Date 02.10.2019
IPC
A61K 9/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
16Agglomerates; Granulates; Microbeadlets
G01N 33/76 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
74involving hormones
76Human chorionic gonadotropin
CPC
A61K 9/1641
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1605Excipients; Inactive ingredients
1629Organic macromolecular compounds
1641obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
Applicants
  • INNOCORE TECHNOLOGIES B.V. [NL]/[NL]
  • MHB LABS, INC. [US]/[US]
Inventors
  • ZUIDEMA, Johan
  • STEENDAM, Rob
  • ARAUJO, Joana Catarina Ribeiro
  • KACKER, Ravi
  • MORGENTALER, Abraham
Agents
  • WITMANS, H.A.
Priority Data
62/740,14502.10.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) EXTENDED RELEASE FORMULATIONS OF HUMAN CHORIONIC GONADOTROPIN (HCG)
(FR) FORMULATIONS À LIBÉRATION PROLONGÉE DE GONADOTROPHINE CHORIONIQUE HUMAINE (HCG)
Abstract
(EN)
The present disclosure relates to extended release dosage forms of human chorionic gonadotropin (h CG) or derivatives or isoforms thereof. The extended release h CG dosage forms comprise biodegradable polymer microspheres and provide for extended release of h CG over a desired time period.
(FR)
La présente invention concerne des formes posologiques à libération prolongée de gonadotrophine chorionique humaine (hCG) ou de dérivés ou d'isoformes de celle-ci. Les formes posologiques de hCG à libération prolongée comprennent des microsphères polymères biodégradables et permettent une libération prolongée de hCG sur une période de temps souhaitée.
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