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1. WO2020070732 - ORAL COMPOSITION COMPRISING Β-ESCIN AND THE USE THEREOF

Publication Number WO/2020/070732
Publication Date 09.04.2020
International Application No. PCT/IB2019/058529
International Filing Date 07.10.2019
IPC
A61K 31/704 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034attached to a carbocyclic compound, e.g. phloridzin
704attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
C07H 15/256 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
20Carbocyclic rings
24Condensed ring systems having three or more rings
256Polyterpene radicals
A61P 3/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
A61K 36/73 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
CPC
A61K 31/704
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034attached to a carbocyclic compound, e.g. phloridzin
704attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
A61K 36/73
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
A61K 36/77
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
77Sapindaceae (Soapberry family), e.g. lychee or soapberry
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
Applicants
  • ESCILAB SP Z O. O. [PL]/[PL]
Inventors
  • KOZIAK, Katarzyna
Agents
  • ŻEBROWSKA-KUCHARZYK, Agnieszka
Priority Data
P.42731005.10.2018PL
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ORAL COMPOSITION COMPRISING Β-ESCIN AND THE USE THEREOF
(FR) COMPOSITION ORALE COMPRENANT DE LA β-ESCINE ET UTILISATION ASSOCIÉE
Abstract
(EN)
The present invention relates to a field of treatment and prevention of overweight and obesity. In particular the present invention is directed to an oral composition comprising (beta)-escin (beta-escin) for use in prevention of extracellular to intracellular water ratio (ECW/ICW) increase in weight loss interventions in treatment of overweight and obesity. Therefore, the composition of the invention has a beneficial effect on fluid distribution during weight loss. The composition of the invention not only improves ECW/ICW ratio but also induces an anorectic effect and results in appetite suppression. Therefore, it is useful alone as overweight and obesity intervention.
(FR)
La présente invention porte sur le domaine du traitement et de la prévention contre le surpoids et l'obésité. En particulier, la présente invention concerne une composition orale comprenant de la β-escine (bêta-escine) utilisée pour prévenir l'augmentation du rapport extracellulaire/intracellulaire (ECW/ICW) lors d'interventions de perte de poids dans le cadre d'un traitement contre le surpoids ou l'obésité. Par conséquent, la composition de l'invention a un effet bénéfique sur la distribution de fluide pendant la perte de poids. La composition de l'invention améliore non seulement le rapport ECW/ICW, mais induit également un effet anorexigène et entraîne une suppression de l'appétit. Ainsi, la présente invention peut être utilisée seule, efficacement, en tant qu'intervention contre le surpoids ou l'obésité à part entière.
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