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1. WO2020069507 - ANTI-HUMAN VSIG4 ANTIBODIES AND USES THEREOF

Publication Number WO/2020/069507
Publication Date 02.04.2020
International Application No. PCT/US2019/053824
International Filing Date 30.09.2019
IPC
C07K 16/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C07K 14/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
G01N 33/00 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
A61K 47/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
CPC
C07K 16/2803
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
C07K 2317/24
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
20characterized by taxonomic origin
24containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
C07K 2317/52
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
50characterized by immunoglobulin fragments
52Constant or Fc region; Isotype
C07K 2317/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
50characterized by immunoglobulin fragments
56variable (Fv) region, i.e. VH and/or VL
C07K 2317/92
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
90characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
G01N 33/00
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
Applicants
  • EUTILEX CO., LTD. [KR]/[KR]
  • KWON, Byoung S. [KR]/[KR]
  • KIM, Hye Jeong [KR]/[KR]
  • HWANG, Sunhee [KR]/[KR]
  • LEE, Joongwon [KR]/[KR]
  • LEE, Seunghyun [KR]/[KR]
  • IM, Sun-woo [KR]/[KR]
  • CHOI, Jinkyung [KR]/[KR]
  • SON, Hyuntae [KR]/[KR]
  • PARK, Hyeok-Jun [KR]/[US]
Inventors
  • KWON, Byoung S.
  • KIM, Hye Jeong
  • HWANG, Sunhee
  • LEE, Joongwon
  • LEE, Seunghyun
  • IM, Sun-woo
  • CHOI, Jinkyung
  • SON, Hyuntae
  • PARK, Hyeok-Jun
Agents
  • WON, Doyon
  • LAVOIE, Teresa A.
Priority Data
62/738,25528.09.2018US
62/776,52307.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-HUMAN VSIG4 ANTIBODIES AND USES THEREOF
(FR) ANTICORPS ANTI-VSIG4 HUMAINS ET LEURS UTILISATIONS
Abstract
(EN)
Provided are antibodies and antigen-binding fragment thereof that bind to VSIG4. Various in vitro and in vivo methods and compositions related to antibodies. Methods include prevention and/or therapeutic treatment of cancer using an antibody or an antigen-binding fragment that binds to VSIG4.
(FR)
L'invention concerne des anticorps et un fragment de liaison à l'antigène associé qui se lient à VSIG4. L'invention concerne également diverses méthodes et compositions in vitro et in vivo associées aux anticorps. Les méthodes comprennent la prévention et/ou le traitement thérapeutique du cancer à l'aide d'un anticorps ou d'un fragment de liaison à l'antigène qui se lie à VSIG4.
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