Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020069222 - TOPICAL NEUROTOXIN COMPOSITIONS

Publication Number WO/2020/069222
Publication Date 02.04.2020
International Application No. PCT/US2019/053301
International Filing Date 26.09.2019
IPC
A61K 9/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
A61K 31/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
14Quaternary ammonium compounds, e.g. edrophonium, choline
A61K 47/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
CPC
A61K 38/4893
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
46Hydrolases (3)
48acting on peptide bonds (3.4)
4886Metalloendopeptidases (3.4.24), e.g. collagenase
4893Botulinum neurotoxin (3.4.24.69)
A61K 47/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 9/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
Applicants
  • GLOBAL HEALTH SOLUTIONS LLC [US]/[US]
Inventors
  • BURNAM, Bradley
Agents
  • DAVIS, Kevin J.
  • WEAVER, Andrew Z.
Priority Data
62/736,61126.09.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TOPICAL NEUROTOXIN COMPOSITIONS
(FR) COMPOSITIONS DE NEUROTOXINES TOPIQUES
Abstract
(EN)
Lipid-based topical neurotoxin compositions and methods of treatment using the same. The lipid-based compositions may include a lipid carrier, a polar solvent, and a neurotoxin soluble in the polar solvent. The lipid-based topical neurotoxin compositions are capable of transdermal delivery of neurotoxins, such as botulinum neurotoxin, to the muscles below the skin. Methods of treatment using the presently disclosed compositions are provided, including methods for the treatment or prevention of facial creases, migraine headaches, hyperhidrosis, cervical dystonia, focal spasticity, and blepharospasm.
(FR)
L'invention concerne des compositions de neurotoxines topiques à base de lipides et des méthodes de traitement faisant appel à celles-ci. Les compositions à base de lipides peuvent comprendre un vecteur lipidique, un solvant polaire et une neurotoxine soluble dans le solvant polaire. Les compositions de neurotoxines topiques à base de lipides sont aptes à l'administration transdermique de neurotoxines, telles que la neurotoxine botulique, aux muscles sous la peau. L'invention concerne également des méthodes de traitement faisant appel aux compositions présentement décrites, notamment des méthodes pour le traitement ou la prévention de rides du visage, de maux de tête migraineux, d'hyperhidrose, de dystonie cervicale, de spasticité focale et de blépharospasme.
Latest bibliographic data on file with the International Bureau