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1. WO2020066188 - WATER-CONTAINING TRANSDERMAL PATCH

Publication Number WO/2020/066188
Publication Date 02.04.2020
International Application No. PCT/JP2019/025673
International Filing Date 27.06.2019
IPC
A61K 9/70 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
A61K 47/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
02Inorganic compounds
A61K 47/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen
12Carboxylic acids; Salts or anhydrides thereof
A61K 47/32 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
CPC
A61K 47/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
02Inorganic compounds
A61K 47/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
12Carboxylic acids; Salts or anhydrides thereof
A61K 47/32
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers ; , poly(meth)acrylates, or polyvinyl pyrrolidone
A61K 9/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
Applicants
  • ニチバン株式会社 NICHIBAN CO., LTD. [JP]/[JP]
Inventors
  • 丹羽 勝久 NIWA, Katsuhisa
  • 金箱 眞 KANEBAKO, Makoto
Agents
  • 特許業務法人はなぶさ特許商標事務所 HANABUSA PATENT & TRADEMARK OFFICE
Priority Data
2018-18041326.09.2018JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) WATER-CONTAINING TRANSDERMAL PATCH
(FR) TIMBRE TRANSDERMIQUE CONTENANT DE L'EAU
(JA) 含水系貼付剤
Abstract
(EN)
[Problem] To provide a water-containing transdermal patch in which adhesive strength is maintained even after moisture in an adhesive layer has evaporated. [Solution] This water-containing transdermal patch contains an alkyl acrylate ester-based copolymer in an adhesive layer. The alkyl acrylate ester-based copolymer is a copolymer of a monomer mixture comprising a monomer A and a monomer B. The monomer A is a monomer that gives a polymer having a glass transition temperature (Tg) of 270 K or higher when the monomer A is homopolymerized. The monomer B is a monomer that gives a polymer having a glass transition temperature (Tg) of 220 K or lower when the monomer B is homopolymerized. The proportion of the monomer A is 30-50 mass% relative to the overall mass of the monomer mixture.
(FR)
La présente invention a pour but de fournir un timbre transdermique contenant de l'eau dont la force adhésive est conservée même après l'évaporation de l'humidité présente dans une couche adhésive. La solution de l'invention porte sur un timbre transdermique contenant de l'eau qui contient un copolymère à base d'ester d'acrylate d'alkyle dans une couche adhésive. Le copolymère à base d'ester d'acrylate d'alkyle est un copolymère constitué d'un mélange de monomères comprenant un monomère A et un monomère B. Le monomère A est un monomère qui donne un polymère ayant une température de transition vitreuse (Tv) de 270 K ou plus lorsque le monomère A est homopolymérique. Le monomère B est un monomère qui donne un polymère ayant une température de transition vitreuse (Tv) de 220 K ou moins lorsque le monomère B est homopolymérique. La proportion du monomère A est de 30 à 50 % en masse par rapport à la masse totale du mélange de monomères.
(JA)
【課題】粘着剤層中の水分が揮散した後においても粘着力が持続する含水系貼付剤を提供すること。 【解決手段】モノマーAとモノマーBからなるモノマー混合物の共重合体であるアクリル酸アルキルエステル系共重合体であって、前記モノマーAは、該モノマーAをホモ重合したときガラス転移温度(Tg)が270K以上のポリマーとなるモノマーであり、前記モノマーBは、該モノマーBをホモ重合したときガラス転移温度(Tg)が220K以下のポリマーとなるモノマーであり、前記モノマー混合物の全質量に対して、前記モノマーAの割合が30質量%以上50質量%以下の割合である、アクリル酸アルキルエステル系共重合体を粘着剤層に配合してなる含水系貼付剤。
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