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1. WO2020065667 - NOVEL POLYMORPHS OF ACALABRUTINIB, A BRUTON'S TYROSINE KINASE INHIBITOR

Publication Number WO/2020/065667
Publication Date 02.04.2020
International Application No. PCT/IN2019/050696
International Filing Date 24.09.2019
IPC
C07D 487/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 31/4985 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • CIPLA LIMITED [IN]/[IN]
Inventors
  • MALHOTRA, Geena
  • PULLELA, Venkata Srinivas
  • PATHI, Srinivas Laxminarayan
  • CHENNURU, Ramanaiah
  • DEVARAPALLI, Ramesh
  • MITHUN, Ashok
Agents
  • P., Aruna Sree
Priority Data
20182103610225.09.2018IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL POLYMORPHS OF ACALABRUTINIB, A BRUTON'S TYROSINE KINASE INHIBITOR
(FR) NOUVEAUX POLYMORPHES D'ACALABRUTINIB, UN INHIBITEUR DE LA TYROSINE KINASE DE BRUTON
Abstract
(EN)
The present invention discloses novel crystalline polymorphic forms of Acalabrutinib, methods of preparation, pharmaceutical compositions and methods of therapeutic treatment involving polymorphic forms thereof.
(FR)
La présente invention concerne de nouvelles formes polymorphes cristallines d'acalabrutinib, des procédés de préparation, des compositions pharmaceutiques et des procédés de traitement thérapeutique impliquant des formes polymorphes de celui-ci.
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