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1. WO2020065475 - TITLE: PROCESS FOR THE PREPARATION OF BILASTINE

Publication Number WO/2020/065475
Publication Date 02.04.2020
International Application No. PCT/IB2019/057967
International Filing Date 20.09.2019
IPC
C07D 401/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
A61K 31/445 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
CPC
A61K 31/445
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
445Non condensed piperidines, e.g. piperocaine
C07D 401/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
04directly linked by a ring-member-to-ring-member bond
Applicants
  • GLENMARK LIFE SCIENCES LIMITED; GLENMARK PHARMACEUTICALS LIMITED [IN]/[IN]
Inventors
  • BHIRUD, Shekhar Bhaskar
  • KADAM, Suresh Mahadev
  • GAVHANE, Sachin Baban
  • KHANDAGALE, Sadeep Bandu
  • MINDHE, Ajit Shankar
  • DWIVEDI, Rajesh Kumar
  • SINHA, Sukumar
Priority Data
20182103602425.09.2018IN
20182104931327.12.2018IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TITLE: PROCESS FOR THE PREPARATION OF BILASTINE
(FR) PROCÉDÉ POUR LA PRÉPARATION DE BILASTINE
Abstract
(EN)
The present invention relates to a process for the preparation of bilastine, a compound of formula I. The present invention relates to p-xylene solvate of bilastine and process for its preparation. The present invention relates to a process for the preparation of bilastine form 2 via p-xylene solvate of bilastine.
(FR)
La présente invention concerne un procédé de préparation de bilastine, un composé de formule I. La présente invention concerne un solvate de p-xylène de bilastine et son procédé de préparation. La présente invention concerne un procédé de préparation de la forme 2 de bilastine par l'intermédiaire d'un solvate de p-xylène de bilastine.
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