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1. WO2020064188 - PHARMACEUTICAL COMPOSITION COMPRISING SOLID DISPERSIONS OF AMORPHOUS CLADRIBINE AND PHARMACEUTICALLY ACCEPTABLE WATER-SOLUBLE CARRIER

Publication Number WO/2020/064188
Publication Date 02.04.2020
International Application No. PCT/EP2019/071061
International Filing Date 06.08.2019
IPC
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61K 9/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
A61K 9/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
16Agglomerates; Granulates; Microbeadlets
A61K 31/7076 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
CPC
A61K 31/7076
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
A61K 9/146
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
146with organic macromolecular compounds
A61K 9/205
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2022Organic macromolecular compounds
205Polysaccharides, e.g. alginate, gums; Cyclodextrin
Applicants
  • SYNBIAS PHARMA AG [CH]/[CH]
Inventors
  • MATHA, Vladimir
  • ZABUDKIN, Oleksandr
  • ROST, Michael
  • ŘEHÁČKOVÁ, Zdeňka
Agents
  • BERGER, Axel
Priority Data
18196664.925.09.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION COMPRISING SOLID DISPERSIONS OF AMORPHOUS CLADRIBINE AND PHARMACEUTICALLY ACCEPTABLE WATER-SOLUBLE CARRIER
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT DES DISPERSIONS SOLIDES DE CLADRIBINE AMORPHE ET UN EXCIPIENT HYDROSOLUBLE PHARMACEUTIQUEMENT ACCEPTABLE
Abstract
(EN)
The present invention relates to a pharmaceutical composition comprising a solid dispersion of amorphous cladribine and a water-soluble pharmaceutically acceptable carrier, as well as a method for preparing same.
(FR)
La présente invention concerne une composition pharmaceutique comprenant une dispersion solide de cladribine amorphe et un excipient pharmaceutiquement acceptable hydrosoluble, ainsi que son procédé de préparation.
Also published as
Latest bibliographic data on file with the International Bureau