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1. WO2020063553 - BIFIDOBACTERIUM LACTIS BL-99 AND APPLICATION THEREOF

Publication Number WO/2020/063553
Publication Date 02.04.2020
International Application No. PCT/CN2019/107392
International Filing Date 24.09.2019
IPC
C12N 1/20 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
A61K 35/74 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
A61P 19/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
A61P 37/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C12R 1/225 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1Microorganisms
01Bacteria or actinomycetales
225Lactobacillus
CPC
A61K 35/74
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
A61P 19/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
A61P 37/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
C12N 1/20
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof
20Bacteria
C12R 1/225
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
RPROCESSES USING MICROORGANISMS
1Processes using microorganisms
01using bacteria or actinomycetales
225Lactobacillus
Applicants
  • 内蒙古伊利实业集团股份有限公司 INNER MONGOLIA YILI INDUSTRIAL GROUP CO., LTD. [CN]/[CN]
Inventors
  • 刘伟贤 LIU, Wei-Hsien
  • 赵雯 ZHAO, Wen
  • 洪维鍊 HUNG, Wei-Lian
  • 孙婷 SUN, Ting
  • 司徒文佑 SZETO, Ignatius Man-Yau
  • 冯昊天 FENG, Haotian
  • 韦斯科姆·菲利普·A WESCOMBE, Philip Andrew
  • 李昊虬 LI, Haoqiu
Agents
  • 北京三友知识产权代理有限公司 BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD.
Priority Data
201811161053.630.09.2018CN
201811161107.930.09.2018CN
201811161108.330.09.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) BIFIDOBACTERIUM LACTIS BL-99 AND APPLICATION THEREOF
(FR) BIFIDOBACTERIUM LACTIS BL-99 ET APPLICATION ASSOCIÉE
(ZH) 一种乳双歧杆菌BL-99及其应用
Abstract
(EN)
Provided are bifidobacterium lactis BL-99 capable of improving immunity and application thereof. The Bifidobacterium lactis BL-99 was deposited in the China General Microorganisms Collection Management Center (CGMCC) on April 26, 2018 with a deposit number of CGMCC No. 15650, has gastric acid resistance and intestinal fluid resistance, can significantly promote the growth of bifidobacteria and lactic acid bacteria, can significantly increase antibody-producing cells and half hemolysis value HC 50 , activate NK cell activity, can be used for preparing foods that improve immunity, and has the effects of preventing osteoporosis and improving blood calcium and/or phosphorus ions.
(FR)
L'invention concerne bifidobacterium lactis BL-99 capable d'améliorer l'immunité et une application associée. Bifidobacterium lactis BL-99 a été déposée au Centre général chinois de gestion de collecte de micro-organismes (CGMCC) le 26 avril 2018 avec un numéro de dépôt CGMCC No. 15650, présente une résistance à l'acide gastrique et une résistance aux liquides intestinaux, peut favoriser de manière significative la croissance de bifidobactéries et de bactéries lactiques, peut augmenter de manière significative le taux de cellules productrices d'anticorps et la valeur de demi-hémolyse HC50, active l'activité des cellules tueuses naturelles, peut être utilisée pour préparer des aliments qui améliorent l'immunité, et présente les effets de prévention de l'ostéoporose et d'amélioration des taux d'ions calcium et/ou phosphore dans le sang.
(ZH)
提供了一种可提高免疫力的乳双歧杆菌(Bifidobacteriumlactis)BL-99及其应用。所述乳双歧杆菌BL-99,于2018年4月26日保藏于中国普通微生物菌种保藏管理中心CGMCC,保藏编号为CGMCC No.15650,其具有耐胃酸和耐肠液性能,能显著促进双歧杆菌和乳酸菌的生长,且能显著提高抗体生成细胞和半数溶血值HC 50,激活NK细胞活性,可以用于制备提高免疫力的食品等,并具有预防骨质疏松、提高血液的钙离子和/或磷离子等功效。
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