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1. WO2020063262 - APPLICATION OF 3'-DEOXYINOSINE IN PREPARATION OF DRUG, FOOD OR HEALTH PRODUCT FOR MULTIPLE DISEASE

Publication Number WO/2020/063262
Publication Date 02.04.2020
International Application No. PCT/CN2019/103929
International Filing Date 02.09.2019
IPC
A61K 31/708 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
708having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
A61P 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
A61P 3/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
06Antihyperlipidemics
A61P 3/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
A61P 19/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
A61K 8/60 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
60Sugars; Derivatives thereof
CPC
A23L 33/10
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
A23L 33/13
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
13Nucleic acids or derivatives thereof
A23V 2002/00
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2002Food compositions, function of food ingredients or processes for food or foodstuffs
A61K 31/708
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
708having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
A61K 8/60
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
60Sugars; Derivatives thereof
A61K 8/606
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
60Sugars; Derivatives thereof
606Nucleosides; Nucleotides; Nucleic acids
Applicants
  • SHENZHEN SUNNY BIO-TECHNOLOGY.CO., LTD [CN]/[CN]
Inventors
  • TANG, Xudong
  • LIU, Rui
  • XU, Jianyi
  • WANG, Hongjuan
  • ZHANG, Jingzhao
  • ZHOU, Yanli
Agents
  • BEIJING GAOWO LAW FIRM
Priority Data
201811157346.730.09.2018CN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) APPLICATION OF 3'-DEOXYINOSINE IN PREPARATION OF DRUG, FOOD OR HEALTH PRODUCT FOR MULTIPLE DISEASE
(FR) APPLICATION DE LA 3'-DÉSOXYINOSINE DANS LA PRÉPARATION D'UN MÉDICAMENT, D'UN ALIMENT OU D'UN PRODUIT CONCERNANT LA SANTÉ DESTINÉS À DE MULTIPLES MALADIES
Abstract
(EN)
The present invention relates to the field of drug, provides an application of 3'-deoxyinosine in the preparation of food, drug or health products for the prevention or treatment of diet-induced obesity or hyperlipidemia, provides an application of 3'-deoxyinosine in the preparation of food, drug or health products for the prevention of hypertension or arteriosclerosis, and further provides an application of 3'-deoxyinosine in the preparation of skin care products. Studies of the present invention have indicated that 3'-deoxyinosine plays a significant role in treating hyperlipidemia and reducing weights of patients with diet-induced obesity, overcoming the existing technical prejudice. Moreover, 3'-deoxyinosine has a more extensive effect on preventing or treating hyperlipidemia compared with the existing medications. Meanwhile, 3'-deoxyinosine is able to effectively prevent the development of hypertension and arteriosclerosis by reducing serum lipid content and high-density lipoprotein (HDL) content.
(FR)
La présente invention concerne le domaine du médicament et plus particulièrement une application de la 3'-désoxyinosine dans la préparation d'aliments, de médicaments ou de produits concernant la santé pour la prévention ou le traitement de l'obésité induite par le régime alimentaire ou de l'hyperlipidémie, une application de la 3'-désoxyinosine dans la préparation d'aliments, de médicaments ou de produits concernant la santé pour la prévention de l'hypertension ou de l'artériosclérose, ainsi qu'une application de la 3'-désoxyinosine dans la préparation de produits de soin de la peau. Des études de la présente invention ont montré que la 3'-désoxyinosine jouait un rôle important dans le traitement de l'hyperlipidémie et dans la perte de poids de patients atteints d'obésité induite par le régime alimentaire, résolvant le préjudice technique existant. De plus, la 3'-désoxyinosine présente un effet plus large sur la prévention ou le traitement de l'hyperlipidémie par rapport aux médicaments existants. Parallèlement, la 3'-désoxyinosine est capable d'empêcher efficacement le développement de l'hypertension et de l'artériosclérose par diminution de la concentration sérique en lipides et en lipoprotéines de haute densité (HDL).
Also published as
Latest bibliographic data on file with the International Bureau