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1. WO2020031099 - COMPOSITION CONTAINING A MUCOLYTIC AGENT FOR THE TREATMENT OF MUCUS HYPERSECRETION AND A DEVICE FOR THE DOSING THEREOF

Publication Number WO/2020/031099
Publication Date 13.02.2020
International Application No. PCT/IB2019/056710
International Filing Date 07.08.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15
Inhalators
A61K 9/00 (2006.01)
A61K 47/26 (2006.01)
A61K 47/36 (2006.01)
A61K 31/00 (2006.01)
A61M 15/00 (2006.01)
Applicants
  • SOFAR S.P.A. [IT/IT]; Via Firenze 40 20060 Trezzano Rosa [MI], IT
Inventors
  • BIFFI, Andrea; IT
Agents
  • HOFFMANN EITLE S.R.L.; Piazza Sigmund Freud 1 Torre 2, Piano 22 20154 Milano, IT
  • ZANGS, Rainer E.; IT
  • KINDLER, Matthias; IT
  • FRANK, Veit Peter; IT
  • POLZ, Leo; IT
  • STEIN-DRÄGER, Christiane; IT
  • AVERY, Stephen John; IT
  • LETHEM, David James; IT
  • MARSH, Roy David; IT
  • MITCHELL, Alan; IT
  • FURLONG, Christopher Heinrich; IT
  • BAUSCH, Thorsten; IT
  • TAORMINO, Joseph Paul; IT
  • KLUSMANN, Peter; IT
  • SCHWEIGHART, Peter; IT
  • WOLF, Matthias; IT
  • SIEGERT, Georg; IT
  • MAYRHOFER, Stefan; IT
  • STRATMANN, Klemens; IT
  • WIEDEMANN, Peter; IT
  • VON KUROWSKI, Lorenz; IT
  • BECHER, Claus Thomas; IT
  • SPILGIES, Jan-Hendrik; IT
  • RENKEN, Joachim; IT
  • ENGELHARD, Elisabeth; IT
  • BACHELIN, Karl Martin Raimund; IT
  • DISSER, Stephan; IT
  • VAN BOUWELEN, Franciscus Maria; IT
  • FÜCHSLE, Kathrin; IT
  • CIESLA, Ulrike; IT
  • SCHÖN, Anne Katrin; IT
  • VOCKE, Henrik; IT
  • GÖRG, Andreas; IT
  • GARBERG, Morten; IT
  • RUSSELL, John Alistair; IT
  • SPROSTON, David; IT
  • THIRLWELL, Karen; IT
  • SCHEIBLE, Dominik; IT
  • VOS, Bianca-Lucia; IT
  • DOUXCHAMPS, Nicolas; IT
  • STEFFERL, Andreas; IT
  • GOLLER, Daniel; IT
  • PRUSS, Timo; IT
  • WERNER-JONES, Leonard L.; IT
  • BACCELLI, Michele; IT
  • MÜLLER, Markus Georg; IT
  • MUNCKE, Nadja; IT
  • CORNEO, Giovanni; IT
  • STREGE, Christine; IT
  • DRAGOSAVAC, Marko; IT
  • BIRKETT, Matthew; IT
  • ZILLIES, Jan Carl; IT
  • GROHS, Daniel; IT
  • MULHERN, Declan; IT
  • GRIMM, Stephan; IT
  • TILLMANN, Volker; IT
  • OGLE, James Matthew; IT
  • GLAS, Johannes Dominik; IT
  • STEINMÜLLER, Stephan; IT
  • BENEDETTO, Marco; IT
  • LEVINE, Benjamin; IT
  • JONES, Mark A. G.; IT
  • GRAEBER, Jens; IT
  • FUSTER, Gustavo; IT
  • ESSER, Axel T.; IT
  • SCHIEREN, Roland; IT
  • RECKENTHÄLER, Peter; IT
  • CATANIA, Olivier; IT
  • DÖRFEL, Katrin; IT
  • WEINMANN, Lasse; IT
  • SASSE, Stefan; IT
  • MACHOTTA, Axel; IT
  • SCHREIBER, Christian; IT
  • WYDER, Thomas; IT
  • WEIGEL-KRUSEMARCK, Michaela; IT
  • MÜLLER, Michael; IT
  • LEWIS, Debra Louise; IT
  • PAETZOLD, Helge; IT
  • SPIRKOSKA, Danche; IT
Priority Data
10201800000792807.08.2018IT
Publication Language English (EN)
Filing Language Italian (IT)
Designated States
Title
(EN) COMPOSITION CONTAINING A MUCOLYTIC AGENT FOR THE TREATMENT OF MUCUS HYPERSECRETION AND A DEVICE FOR THE DOSING THEREOF
(FR) COMPOSITION CONTENANT UN AGENT MUCOLYTIQUE POUR LE TRAITEMENT DE L'HYPERSÉCRÉTION DE MUCUS ET DISPOSITIF POUR LE DOSAGE DE CELLE-CI
Abstract
(EN)
The present invention regards a composition in powder form for oral inhalation, preferably for oral aspiration, comprising a mucolytic agent, preferably N-acetylcysteine. Furthermore, the present invention regards said composition for use in a method for the treatment of a mucus hypersecretion and of diseases, symptoms or disorders associated with it in a needy subject. Lastly, the present invention regards a device for administration, through inhalation route by means of oral aspiration, to said needy subject.
(FR)
La présente invention concerne une composition sous forme de poudre pour inhalation orale, de préférence pour une aspiration orale, comprenant un agent mucolytique, de préférence la N-acétylcystéine. En outre, la présente invention concerne ladite composition destinée à être utilisée dans un procédé de traitement d'une hypersécrétion de mucus et de maladies, de symptômes ou de troubles associés à celle-ci chez un sujet nécessitant un tel traitement. Enfin, la présente invention concerne un dispositif d'administration, par voie d'inhalation au moyen d'une aspiration orale, audit sujet nécessitant un tel traitement.
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