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1. WO2020028426 - DIFFUSION ENHANCING COMPOUNDS AND THEIR USE WITH THROMBECTOMY AND EMBOLECTOMY AND OTHER VASCULAR DISEASE PROCEDURES

Publication Number WO/2020/028426
Publication Date 06.02.2020
International Application No. PCT/US2019/044232
International Filing Date 30.07.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
18
Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
202
having three or more double bonds, e.g. linolenic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
203
Retinoic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
205
Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
10
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
57
Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
02
with only carbon-to-carbon double bonds as unsaturation
13
Dicarboxylic acids
A61B 18/00 (2006.01)
A61K 31/202 (2006.01)
A61K 31/203 (2006.01)
A61K 31/205 (2006.01)
A61P 9/10 (2006.01)
C07C 57/13 (2006.01)
Applicants
  • DIFFUSION PHARMACEUTICALS LLC [US/US]; 1317 Carlton Avenue Suite 200 Charlottesville, Virginia 22902, US
Inventors
  • KALERGIS, David G.; US
  • BYRNE, Thomas; US
Agents
  • JONES, Marya K.; US
Priority Data
62/712,01230.07.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DIFFUSION ENHANCING COMPOUNDS AND THEIR USE WITH THROMBECTOMY AND EMBOLECTOMY AND OTHER VASCULAR DISEASE PROCEDURES
(FR) COMPOSÉS AMÉLIORANT LA DIFFUSION ET LEUR UTILISATION AVEC LA THROMBECTOMIE ET L'EMBOLECTOMIE ET D'AUTRES INTERVENTIONS DE TRAITEMENT DE MALADIES VASCULAIRES
Abstract
(EN)
The subject invention relates to novel methods for the rapid treatment of disorders resulting from thrombosis or embolism such as a myocardial infarction or stroke. Specifically, the invention relates to diffusion enhancing compounds and their use with embolectomy and thrombectomy, or other procedures for the treatment of ischemia.
(FR)
La présente invention concerne de nouveaux procédés pour le traitement rapide de troubles résultant d'une thrombose ou d'une embolie telle qu'un infarctus du myocarde ou un accident vasculaire cérébral. Spécifiquement, l'invention concerne des composés améliorant la diffusion et leur utilisation avec une embolectomie et une thrombectomie, ou d'autres interventions pour le traitement de l'ischémie.
Latest bibliographic data on file with the International Bureau