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1. WO2020008097 - METHOD FOR OBTAINING DATA THAT CAN BE USED FOR THE PREDICTION OR PROGNOSIS OF OVERALL SURVIVAL AND RELAPSE-FREE SURVIVAL FROM CANCER, AND COMPOSITION THAT CAN MODULATE THE ACTIVITY OF ATF4 FOR THE TREATMENT OF CANCER

Publication Number WO/2020/008097
Publication Date 09.01.2020
International Application No. PCT/ES2019/070470
International Filing Date 03.07.2019
IPC
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
C12Q 1/68 (2018.01)
CPC
C12Q 1/68
Applicants
  • UNIVERSIDAD DE GRANADA [ES/ES]; Hospital Real Avda. del Hospicio s/n 18071 Granada, ES
  • SERVICIO ANDALUZ DE SALUD [ES/ES]; Avda. de la Constitución, 18 41071 Sevilla, ES
Inventors
  • GRANADOS PRINCIPAL, Sergio; ES
  • SÁNCHEZ ROVIRA, Pedro; ES
  • RAMÍREZ TORTOSA, César; ES
  • GARCÍA CHÁVES, María Angel; ES
  • MARCHAL CORRALES, Juan Antonio; ES
Priority Data
P20183066503.07.2018ES
P20183066603.07.2018ES
Publication Language Spanish (ES)
Filing Language Spanish (ES)
Designated States
Title
(EN) METHOD FOR OBTAINING DATA THAT CAN BE USED FOR THE PREDICTION OR PROGNOSIS OF OVERALL SURVIVAL AND RELAPSE-FREE SURVIVAL FROM CANCER, AND COMPOSITION THAT CAN MODULATE THE ACTIVITY OF ATF4 FOR THE TREATMENT OF CANCER
(ES) MÉTODO DE OBTENCIÓN DE DATOS ÚTILES PARA PREDECIR O PRONOSTICAR LA SUPERVIVENCIA GLOBAL Y LA SUPERVIVENCIA LIBRE DE RECAÍDAS EN EL CÁNCER Y COMPOSICIÓN CAPAZ DE MODULAR LA ACTIVIDAD DE ATF4 PARA EL TRATAMIENTO DEL CÁNCER
(FR) MÉTHODE D'OBTENTION DE DONNÉES UTILES POUR PRÉDIRE OU PRONOSTIQUER LA SURVIE GLOBALE ET LA SURVIE LIBRE DE RÉCIDIVES POUR LE CANCER ET COMPOSITION POUVANT MODULER L'ACTIVITÉ DU FACTEUR DE TRANSCRIPTION ATF4 POUR LE TRAITEMENT DU CANCER
Abstract
(EN)
The present invention relates to an in vitro method of obtaining data that can be used for the prediction or prognosis of overall survival and relapse-free survival from cancer, preferably breast cancer. In addition, the present invention relates to a composition that can modulate the activity of ATF4 for the treatment of cancer.
(ES)
La presente invención se refiere a un método in vitro de obtención de datos útiles para predecir o pronosticar la supervivencia global y la supervivencia libre de recaídas en el cáncer, preferiblemente cáncer de mama. Además, la presente invención se refiere a una composición capaz de modular la actividad de la ATF4 para el tratamiento del cáncer.
(FR)
La présente invention concerne une méthode in vitro d'obtention de données utiles pour prédire ou pronostiquer la survie globale et la survie libre de récidives pour le cancer, de préférence le cancer du sein. L'invention concerne en outre une composition pouvant moduler l'activité du facteur de transcription ATF4 pour le traitement du cancer.
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