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1. WO2020007346 - NEW CRYSTALLINE FORM PRODUCT OF UREA COMPOUND AND PREPARATION METHOD THEREFOR

Publication Number WO/2020/007346
Publication Date 09.01.2020
International Application No. PCT/CN2019/094744
International Filing Date 04.07.2019
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
C07D 471/04 (2006.01)
A61K 31/395 (2006.01)
A61P 35/00 (2006.01)
CPC
A61K 31/395
A61P 35/00
C07D 471/04
Applicants
  • 成都华健未来科技有限公司 CHENGDU HUAJIAN FUTURE TECHNOLOGY CO., LTD. [CN/CN]; 中国四川省成都市 温江区永宁镇八一路北段18号(三医创新中心)1号楼4单元 18 North Bayi Road, Tri-Med Innovation Center Building 1 Unit 4, Yongning Town, Wenjiang District, Chengdu, Sichuan 611130, CN
Inventors
  • 张磊 ZHANG, Lei; CN
Agents
  • 北京信诺创成知识产权代理有限公司 SINO-CREATIVITY INTELLECTUAL PROPERTY LAW FIRM; 中国北京市 朝阳区光华路7号汉威大厦东区25A3-1室 Room 25A3-1, East Wing, Hanwei Plaza, No.7 Guanghua Road, Chaoyang District, Beijing 100020, CN
Priority Data
201810733075.905.07.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) NEW CRYSTALLINE FORM PRODUCT OF UREA COMPOUND AND PREPARATION METHOD THEREFOR
(FR) NOUVEAU PRODUIT DE FORME CRISTALLINE D’UN COMPOSÉ D'URÉE ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
(ZH) 一种脲类化合物的新型晶型产品及制备方法
Abstract
(EN)
The present invention specifically relates to a new crystalline form of a urea compound and a preparation method therefor. The crystalline form product has a high solubility in water. The preparation method is simple and has a high yield. The product has stable properties, and is easy to store and transport and later use. The preparation method provided in the present invention has good repeatability in the process, and simple operation, and is suitable for industrial production.
(FR)
La présente invention concerne particulièrement une nouvelle forme cristalline d'un composé d'urée et un procédé de préparation associé. Le produit de forme cristalline a une solubilité élevée dans l'eau. Le procédé de fabrication est simple et présente un rendement élevé. Le produit a des propriétés stables, et est facile à stocker, à transporter et à utiliser ultérieurement. Le procédé de préparation selon la présente invention a une bonne aptitude à la reproduction dans le processus, un mode opératoire simple, et est approprié pour une production industrielle.
(ZH)
本发明具体涉及一种脲类化合物的新晶型及其制备方法,该晶型产品水中溶解度高,制备方法简单,产率高,性质稳定,易于储藏和运输和后期使用。本发明提供的制备方法工艺重现性好,操作简单,适合工业化生产。
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