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1. WO2020007219 - CRYSTALLINE FORM OF EGFR INHIBITOR AND PREPARATION METHOD THEREFOR

Publication Number WO/2020/007219
Publication Date 09.01.2020
International Application No. PCT/CN2019/092987
International Filing Date 26.06.2019
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
498
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
10
Spiro-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
C07D 498/10 (2006.01)
A61K 31/505 (2006.01)
A61P 35/00 (2006.01)
CPC
A61K 31/505
A61P 35/00
C07D 498/10
Applicants
  • 南京明德新药研发有限公司 MEDSHINE DISCOVERY INC. [CN/CN]; 中国江苏省南京市 南京高新开发区高新路9号商务办公室218室 Room 218, No.9 Gaoxin Road, Gaoxin Development District Nanjing, Jiangsu 210032, CN
Inventors
  • 刘希乐 LIU, Xile; CN
  • 张路 ZHANG, Lu; CN
  • 丁照中 DING, Charles Z.; CN
  • 陈曙辉 CHEN, Shuhui; CN
  • 胡利红 HU, Lihong; CN
Agents
  • 上海弼兴律师事务所 SHANGHAI BESHINING LAW OFFICE; 中国上海市 小木桥路681号外经大厦21楼 21st Floor, SFECO Mansion 681 Xiaomuqiao Road Shanghai 200032, CN
Priority Data
201810708913.702.07.2018CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) CRYSTALLINE FORM OF EGFR INHIBITOR AND PREPARATION METHOD THEREFOR
(FR) FORME CRISTALLINE D'INHIBITEUR D'EGFR ET SON PROCÉDÉ DE PRÉPARATION
(ZH) 一种EGFR抑制剂的晶型及其制备方法
Abstract
(EN)
Disclosed in the present invention are a crystalline form of an EGFR inhibitor and a preparation method therefor, and further comprised is an application of the crystalline form in preparing a drug for treating non-small cell lung cancer.
(FR)
La présente invention concerne une forme cristalline d'un inhibiteur d'EGFR et son procédé de préparation, ainsi qu'une application de la forme cristalline dans la préparation d'un médicament pour le traitement du cancer du poumon non à petites cellules.
(ZH)
本发明公开了一种EGFR抑制剂的晶型及其制备方法,还包括所述晶型在制备治疗非小细胞肺癌药物中的应用。
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