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1. (WO2020006508) OVERPOWERED ABA RECEPTOR AGONISTS
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2020/006508 International Application No.: PCT/US2019/039978
Publication Date: 02.01.2020 International Filing Date: 28.06.2019
IPC:
A01N 43/80 (2006.01) ,A61K 31/4439 (2006.01) ,A61K 31/444 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43
Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
72
having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms
80
five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
4439
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
444
containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin St., 12th Floor Oakland, California 94607-5200, US
Inventors:
CUTLER, Sean R.; US
VAIDYA, Aditya; US
HELANDER, Jonathan; US
Agent:
ZYLSTRA, Eric J.; US
HINSCH, Matthew E.; US
HAO, Joe C.; US
PRESLEY, Andrew D.; US
KUSHA, Babak; US
Priority Data:
62/691,53428.06.2018US
Title (EN) OVERPOWERED ABA RECEPTOR AGONISTS
(FR) AGONISTES DE RÉCEPTEURS D'ABA SURCHARGÉS
Abstract:
(EN) The present invention sets forth small novel abscisic acid (ABA) receptor agonist scaffolds and compounds with potent in vivo activity. In some aspects, the present invention provides agricultural formulations and methods comprising the ABA receptor agonists described herein, such as methods of managing crop water use and improving stress tolerance (e.g., drought tolerance). In some preferred embodiments, the inventive compounds have improved properties relative to the current "best in-class" molecules quinabactin and its derivatives.
(FR) La présente invention concerne de nouveaux échafaudages agonistes de récepteurs de l'acide abscissique (ABA) et des composés présentant une puissante activité in vivo. Selon certains aspects, la présente invention concerne des formulations agricoles et des procédés comprenant les agonistes de récepteurs d'ABA décrits dans la présente description, tels que des procédés de gestion de la consommation de l'eau des cultures et d'amélioration de la tolérance au stress (par exemple, la tolérance à la sécheresse). Dans certains modes de réalisation préférés, les composés selon l'invention présentent des propriétés améliorées par rapport aux molécules actuelles de quinabactine qui sont les « meilleures de leur catégorie », et à ses dérivés.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)