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1. WO2020006471 - THERAPEUTIC HYDROGELS AND CONTACT LENS FOR CORNEAL MELTING

Publication Number WO/2020/006471
Publication Date 02.01.2020
International Application No. PCT/US2019/039916
International Filing Date 28.06.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9
Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
08
Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
A61F 9/08 (2006.01)
A61K 31/395 (2006.01)
A61K 31/435 (2006.01)
CPC
A61F 9/0017
A61K 31/395
A61K 31/435
Applicants
  • THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE [US/US]; 1800 Grant Street 8th Floor Denver, Colorado 80203, US
  • UNIVERSITY OF NEW HAMPSHIRE [US/US]; 21 Madbury Road Durham, New Hampshire 03824, US
Inventors
  • LEE, Jung-Jae; US
  • JEONG, Kyung Jae; US
Agents
  • SILVA, Domingos J.; US
  • CROTTY, Justin; US
  • DOYLE, Kathryn; US
  • LANDRY, Brian R.; US
  • LEICHT, Paul; US
  • OSTROVSKY, Dennis; US
  • PLEHN-DUJOWICH, Debora; US
  • SIMPSON, Mark D.; US
  • YOUNG, Jacque; US
Priority Data
62/691,77429.06.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) THERAPEUTIC HYDROGELS AND CONTACT LENS FOR CORNEAL MELTING
(FR) HYDROGELS THÉRAPEUTIQUES ET LENTILLE DE CONTACT CONTRE LA FONTE CORNÉENNE
Abstract
(EN)
The present invention relates to the unexpected discovery of a cross-linked polymer of 2-hydroxyethyl methacrylate and dipicolylamine-containing monomers that can be used as therapeutic lens to treat ocular diseases or disorders associated with MMP over-activity and/or over-expression, such as but not limited to corneal melting (or keratolysis).
(FR)
La présente invention concerne la découverte inattendue d'un polymère réticulé de méthacrylate de 2-hydroxyéthyle et de monomères contenant de la dipicolylamine qui peut être utilisé en tant que lentille thérapeutique pour traiter des maladies ou des troubles oculaires associés à une surexpression et/ou à une suractivité des MMP, tels que, mais non exclusivement, la fonte cornéenne (ou kératolyse).
Latest bibliographic data on file with the International Bureau