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1. WO2020006438 - METHODS OF TREATING OR PREVENTING MUCORMYCOSIS

Publication Number WO/2020/006438
Publication Date 02.01.2020
International Application No. PCT/US2019/039870
International Filing Date 28.06.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
37
from fungi
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
14
against material from fungi, algae or lichens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
10
Antimycotics
A61K 39/395 (2006.01)
C07K 14/37 (2006.01)
C07K 16/14 (2006.01)
A61P 31/10 (2006.01)
CPC
A61K 39/395
A61P 31/10
C07K 14/37
C07K 16/14
Applicants
  • UNIVERSITY OF MARYLAND, BALTIMORE [US/US]; 620 West Lexington Street, 4th Floor Baltimore, MD 21201-1508, US
  • LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR AT [US/US]; UCLA Medical Center 1124 Carson Street Torrance, CA 90502, US
Inventors
  • BRUNO, Vincent; US
  • WATKINS, Tonya, N.; US
  • IBRAHIM, Ashraf; US
Agents
  • NEVRIVY, Daniel, J.; US
Priority Data
62/692,05829.06.2018US
62/772,89329.11.2018US
62/843,80506.05.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF TREATING OR PREVENTING MUCORMYCOSIS
(FR) MÉTHODES DE TRAITEMENT OU DE PRÉVENTION DE LA MUCORMYCOSE
Abstract
(EN)
The invention provides a method of treating or preventing mucormycosis in a subject in need thereof, comprising administering to the subject a therapeutically- effective amount of an agent that inhibits a signaling pathway of a receptor selected from the group consisting of epidermal growth factor receptor, platelet derived growth factor receptor, ErbB2/Her2, progesterone receptor and a combination thereof.
(FR)
L'invention concerne une méthode de traitement ou de prévention de la mucormycose chez un sujet en ayant besoin, comprenant l'administration au sujet d'une quantité thérapeutiquement efficace d'un agent qui inhibe une voie de signalisation d'un récepteur choisi dans le groupe constitué par le récepteur du facteur de croissance épidermique, le récepteur du facteur de croissance dérivé des plaquettes, l'ErbB2/Her2, le récepteur de la progestérone et une combinaison de ceux-ci.
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